Albert Wesker (Anderson)

Loyalty... Highly overrated.

Albert Wesker was the chairman of Umbrella, holding regular meetings from his office in Tokyo via hologram, and heading the Umbrella Committee even during the Global T-virus outbreak. Wesker, just like his game counterpart, serves as the primary antagonist of the film series.

Resident Evil: Extinction
He was constantly at odds with Dr. Isaacs, whose obsession with Project Alice threatened to compromise his appointed task: domesticating the undead. If his work did not show signs of improving, Wesker threatened to replace the doctor with someone more capable. Dr. Isaacs was not perturbed however, and continued to create enhanced zombies to hunt down and capture Alice, an operation that resulted in him being bitten by one of his creations. Having disobeyed direct orders and forged Wesker's authorization, the chairman ordered that he be "liquidated" immediately.

Isaacs' advanced infection transformed him into the first Tyrant however, and he killed everyone inside the Nevada facility. After Isaacs' death at her hands, Alice interrupted a conference between Wesker and the other facility leaders and promised him that she intended to come after him, and she'd be bringing her "a few of her friends" along with her.

Resident Evil: Afterlife
Alice and her clones attack the Umbrella Headquarters in Tokyo and kill everyone in the facility. When alerted to the assault, Wesker orders that all upper levels be flooded with nerve gas to stem the tide of the clones, despite the many who were still locked in combat with them. When a security officer hesitates, Wesker shoots him with his Desert Eagle and inquires to any further questions against his order.

Two clones are killed during the final gambit of the assault on Wesker's facility, both of them by his hands; one shot through the head mid fall, the other shot repeatedly in the chest at close range. The second died with two unpinned grenades in her hand, creating an explosion that burns Wesker's features and forces him to retreat to a helicopter to escape.

As he escapes, the clones attempt to shoot it down but its hull is bulletproof. As he ascends, Wesker activates a "Purge" bomb that destroys the facility, vaporizing part of Tokyo and the clones in process. The real Alice is on board the helicopter however and prepares to kill him. Instead, Wesker quickly injects Alice with a serum that destroys the "T" cells in her body and renders her powerless. Wesker reveals that he has injected himself with the T-Virus too and displays superhuman strength and speed, similar to Alice's former powers. He easily overpowers her and seconds from certain death, Alice thanks him for making her "human again". Thoroughly distracted, Wesker has no time to regain control of the un-piloted helicopter before crashes into a mountainside. Wesker is thought to have died in the crash, while Alice barely survives.

However, Wesker's new powers enable him to regenerate from his injuries; he heads to the Umbrella ship, Arcadia, where he takes command and uses Umbrella's remaining satellites to track Alice. After escaping the Citadel Correctional Facility, Alice, Claire and Chris Redfield make their way to the Arcadia, located in the Los Angeles Harbor. There, they discover over 2,000 humans held in suspended animation for testing. Upon releasing the survivors, Alice discovers two pods drenched in blood and follows the blood trail to Wesker. When she attempts to attack, he calls on two zombie dogs and an armed necrosing Bennett to hold her at bay. Wesker explains that the t-virus is starting to overtake him and believes that eating fresh human tissue will keep it at bay, which is why the Arcadia crew abandoned ship three days prior.

However, if Wesker eats Alice, who had adapted to the t-virus so well, her DNA will allow him to gain full control over himself. Alice tells him that she is "not on the menu" and kicks a tray full of scalpels at Wesker, who dodges all but one (which grazes his right cheek). Before Wesker can retaliate he is confronted by Claire and Chris, prompting Alice to remind him that she promised to bring "friends". Wesker removes his sunglasses, revealing his severely alerted and red eyes, and remarks "You should have brought more". Wesker battles Chris and Claire, his super strength and speed overpowers them easily. He traps them in holding tanks before focusing on Alice, who has killed the dogs and disarmed Bennett.

Wesker produces several mandible-like tentacles from his mouth and prepares to eat her, but she stabs him in the head, temporarily stunning him. Alice tries to retrieve her shotgun to finish the job when Bennett blocks her path. In turn, he is stopped by K-Mart, who knocks him out and tosses Alice the shotgun. Alice shoots Wesker in the head, blowing out the top side of his skull. After freeing Claire and Chris, two who unload their pistols onto a regenerating Wesker at point blank ranger. They seal him and Bennett inside the chamber, Wesker regenerates from his wounds and kills Bennett before making his way to another chopper to escape. He activates another bomb that was placed on the Arcadia, believing it still to be on the ship. However, moments before detonation, he discovers the bomb hidden on the chopper. The bomb detonates, destroying the helicopter.

Resident Evil Retribution
Shawn Roberts will reprise the role of Albert Wesker, as confirmed by Milla Jovovich and IGN.com. This is further supported by the final scene in Afterlife. When Luther is revealed to have survived the zombies, in the scene just before Luther appears, a tiny parachute deploy can be seen in the distance before disappearing into fog. This makes his appearance as a villain in the film the most consistent, having appeared in two of the four films which featured the defeat of the previous villains (Spence, Cain and Isaacs, respectively). As of now, the definition and size of his role is unknown.

Trivia
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 * The movie's version is pretty different from game's version, considering biological elements. Even Robert's version has red cat eyes, agility, super strenght and regeneration, the original version of Wesker does not ingest others and is not infected by the T-virus. Also, in the games Wesker is not a common infected and does not produces mandible-like tentacles from his mouth.
 * The fight between Wesker against the brothers Redfield is very close to Resident Evil 5 fight between Wesker, Chris and Sheva.


 * The character's version portrayed by Roberts also wears the Midnight Outfit from Resident Evil 5 in the battle against Alice and the Redfield brothers.
 * A great difference between the original and the movie version is the role wich Wesker does. In the games, he is an Umbrella's high researcher, but got his own plans of world domination. After injecting Birkin's experimental virus and being considered deceased, Wesker joins the Organization against Umbrella and with useful infromation succeed in throwing the Bio terrorist enterprise into ilegal. Further, he would kill Ozwell E. Spencer, the remaining creator of Umbrella, and could fulfill his plans. In the movie, it's the extreme opposite: Wesker is the chairman of Umbrella, is infected by the T-virus and is never opposite to Umbrella's goals.