Claire Redfield (Operation Raccoon City)

Films
Claire appears in the film series in the third and fourth movies, Extinction and Afterlife.

Resident Evil: Operation Raccoon City
After arriving in town, Claire and Leon were separated due to a crash and extraction for the U.S.S. was postponed in order to investigate the crash site. After encountering Leon, the U.S.S. attempts to eliminate him, but he manages to escape.

After discovering Leon's whereabout in the Umbrella lab, Umbrella agreed to locate Leon and intercepted a distress call from him. They learned that Leon was accompanied by Claire Redfield and Sherry Birkin, and that they have taken refuge at the Londsdale Trainyard. Umbrella informs the U.S.S. about the G antibodies inside of Sherry and instructs them to eliminate Claire and Leon in order to capture Sherry.

After a brief battle with Claire and Leon, the U.S.S. are finally able to catch up with Leon and threaten to kill him if Claire doesn't bring Sherry to them. Though reluctant, Claire agrees to bring Sherry to them.

Eliminate Leon - If the player chooses to eliminate Leon, the U.S.S. will stick to their original plan of killing Claire and Leon. With Leon already dead, the U.S.S. has to finish the job by killing Claire.

Defend Leon - If the player chooses to save Leon, the U.S.S. decides to let Claire, Sherry, and Leon live due to a disagreement with Umbrella. The U.S.S. decides that Leon isn't the leverage they wanted and they let Sherry stay with Claire and Leon.

Claire also appears as a non-playable character in the fourth mission of the Echo Six DLC, Nothing is as it Seems, where Echo Six helps her to find Sherry in the sewers. She is playable in "Heroes mode"