Giant Spider

A Giant Spider is any spider that has been infected due to the t-Virus in an unplanned manner - a biohazardous outbreak. They are different from the Web Spinner in the sense that the Web Spinner B.O.W.s were experimented from the start, while the wild spiders simply mutated on contact. The Giant spiders, like other t-Virus-infected spiders, produce "little spiders", which live on their mother's back.

The Giant Spiders frequented in the sewers of Raccoon City, where they were infected during the Raccoon City Destruction Incident when the t-Virus was leaked into the sewers. In a similar manner, Giant Spiders populated the sewers of Sheena Island two months later during its own viral outbreak.