Pluto

The Pluto was one of Umbrella Pharmaceutical, Inc.'s failed experiments to create their perfect bio-weapon - the Tyrant.

History
Originally a condemned criminal only known as "α" (Alpha), what would become Pluto was subject to numerous experiments.

On the first day of the experiment, a metal rod was hammered into his frontal lobe to alleviate pain. On the fourth day, his eyes were removed to test how his other senses would react.

Later into the experiment, he would gain mass, becoming overweight around the time he was given steroids to improve his muscles. Despite his immense size, he is also incredibly fast and his acute hearing makes him very accurate.

The experiment was suspended on day 41 after "α" managed to escape. He would meet his demise at the hands of Bruce McGivern, a government agent sent to arrest a Bioterrorist.

Strategy
Pluto uses his heightened sense of hearing to find his prey. Upon finding his prey, he will run into them, crushing them with his mass. To avoid him, it is best that you do not run, but instead walk around the crates, confusing him.

Pluto's weak spot is the top of his head, where the exposed brain is easily damaged due to the top of its skull having been removed. It is best that you use the silenced handgun, as the Suppressor will make it hard for him to hear you.

Trivia
In Roman mythology, Pluto was the god of the underworld, one of Umbrella's many nods to classical culture.