Osmund Saddler

If you must know, my name is Osmund Saddler, the master of this fine... religious community.

Osmund Saddler was the leader of a cult operating in rural Spain known as "Los Illuminados" (English: The Enlightened Ones), who sought for world domination through the implantation of a mind-controlling parasite called "Las Plagas" ("The Plagues").

Biography
Some time before 2004, Saddler had converted the local population into his cult, whose original aim was to free the Plaga parasites from the caverns underneath a nearby castle. His plan for Ashley Graham was to impregnate her with one of the parasites and send her back to the United States. She was to then impregnate her father; President Graham, who would then control the nation under Saddler's command.

Saddler encountered Leon S. Kennedy and Ashley frequently, first setting his minions on them, then using his growing power over their Plaga-infected bodies to control their actions. He killed Luis Sera (a researcher who betrayed him) by impaling him with his tentacle tail when he was about to give Leon the pills to suppress the growth of the Plaga in his body along with a sample of a Plaga. Saddler hired Jack Krauser (an old ally of Leon) to dispose of him, but it was later revealed that he didn't fully trust Krauser and was looking for a way to get rid of him. He briefly fought Ada Wong after she helped Leon free Ashley for the final time. Though he was defeated, he still managed to capture her.

The American prevailing is a cliché that only happens in your Hollywood movies! Oh, Mr. Kennedy, you entertain me! To show my appreciation, I will help you awaken from your world of clichés!

Finally, Leon confronted Saddler on a platform high above the island, and after freeing Ada, watched as Saddler transforms himself into a massive, multi-legged monstrosity. Despite Saddler's considerable strength in this form (and ironically fulfilling the cliché), Leon managed to kill him by using a rocket launcher that he once again got from Ada Wong, ending the Los Illuminados' plans once and for all.

Main Game

 * Saddler's weakpoints are the eyeballs on each of the knees on his 4 legs, when shot with any weapon Saddler will be temporarily incapacitated to the ground and become temporarily vulnerable allowing the player to either climb him to stab the eye in his mouth, or the player can choose to shoot it with a high powered weapon. The eyes blink, which renders them invulnerable and it is advisable to use either a shotgun or a TMP to shoot it when the eyes are open as they blink rather quickly.
 * Alternatively, one Hand Grenade or a shot from a Mine Thrower to his original body is enough to stagger him; note that he is immune to Incendiary Grenades.
 * Each eye can only be hit twice. After that, it will be destroyed, and the player will have to shoot the other eyes to incapacitate him. He has 4 eye balls on his knees, 2 on the front legs and 2 on the rear legs
 * If all 4 of Saddler's knee eyes are destroyed, his main eye inside his mouth becomes vulnerable to gunfire, and may be shot to knock Saddler down (this eye is normally closed and armored, unless Saddler is knocked down).
 * The explosive barrels will also instantly incapacitate Saddler if it explodes while near him. Also the 2 platforms near the end of the walkways have steel bars hanging on a crane which if timed right can also incapacitate Saddler if hit.
 * If the player is on the opposite side of the walkway Saddler will either throw steel bars at Leon (which can be avoided by pressing the correct button combination that will flash on the screen), or amazingly jump over there in one bound.
 * It IS possible to kill Saddler by simply unloading all your weapons on his body, but this is very uneconomic, unless you have a weapon with infinite ammunition.
 * After dealing some considerable amount of damage to Saddler, Ada will throw a special rocket launcher to the player which will kill Saddler in one shot. However, it is advised that you use it at the right time, because if you miss, then the game automatically ends with Saddler knocking the player off the balcony.
 * You may shoot Saddler's eye when he is incapacitated and then stab him for double damage, but aim carefully.
 * You can use a PRL to kill him easily.
 * It would be easier to kill Saddler if you have a semi automatic rifle, and a rocket launcher. Hit Saddler in any of his eyes in the legs, and when he is incapacitated, hit it in the main eye with the launcher. You have to aim carefully.

Separate Ways

 * Like Krauser, Saddler is incredibly susceptible to the standard knife attack, and if his attacks are successfully dodged and the player can keep up the barrage of knife slashes, he will be very easily defeated in well under a minute's time.
 * If you choose the firearm route, it will take the player a lot of ammunition and health to draw out his Plaga eye and stab it. Use the Bowgun and shoot at his head to save ammo.
 * If the player doesn't press the correct combination when he strikes down, he will push Ada onto the floor and snap her neck, resulting in an instant death.
 * If the player does not type the right button combination when he swings his tentacle arm at Ada, the player must then shake the joystick to make Saddler release Ada, otherwise he will impale her with his tentacle spike, resulting in an instant death.
 * If the player does not press the correct button combination when he draws back his hand, he will strike Ada with the palm of his hand (as he did to Leon in the cutscene before the fight). This does not result in an instant death, but will drain all the health except for a little, in which any hit will kill Ada. This move is similar to Albert Wesker's force punch ability, except that it is ranged.
 * If he is continually shot with bullet firing weapons such as the Blacktail or the TMP, he will amazingly divert all the bullets that were shot into his body to his hand and shoot them back at Ada just like a normal firearm, thus it is advisable that the Bowgun be used when fighting him.
 * Saddler also appears to be quite athletic and surprisingly stronger than he looks, as when Ada is forced to fight him, he can jump from the bottom floor to the top floor in one jump, clearing the railing. Also, during the fight between Saddler's monster form and Leon, he can clear the gap between the two catwalks without hesitation.
 * If the player has the Chicago Typewriter on hand, killing Saddler will take at best 1 minute if it is done correctly.

Trivia

 * Despite being a Plaga carrier, his pupils are not shown to be red colored like any characteristic of a Plaga carriers. This may be because he is the only carrier of a Master Plaga.
 * Saddler is the first antagonist to have no relationship with Umbrella.