2016 was a common year starting on a Friday.
- Resident Evil Zero HD Remaster, known in Japan as the biohazard 0 HD remaster (バイオハザード0 HDリマスター) is released.
- Origins Collection is released.
- BIOHAZARD the Toon is published in Japan.
- 22 March
- 22 April
- 25 April
- 9 May
The BIOHAZARD ✕ DRAGONPOKER collaboration comes to an end.
- 22 May
The SURVIVE of BIOHAZARD shooting range closes.
- 13 June
Resident Evil 7 Teaser Demo: Beginning Hour is released worldwide.
- 21 June
Resident Evil: Umbrella Corps is released worldwide.
- 30 September
MUSICAL BIOHAZARD ~ Voice of Gaia ~ first appears in theaters.
- 14 October
- 8 November
"The World of Resident Evil 7" concludes with the release of its tenth and final video.