Alex Wesker was a high-ranking Umbrella Pharmaceuticals employee who was part of the Project Wesker eugenics program. In the years following Umbrella's downfall, Wesker took control of a number of islands where she began viral research, one of which ruling over a people that hailed her as the Messiah or even a goddess.[note 2]
"I hope you'll be delighted to know that the experiment's going well."
— Alex, to Spencer
Alex Wesker's early life and true surname are unknown. She was taken from her parents at an early age as part of the Wesker Project, a eugenics project, and renamed after the project leader, Dr. Wesker. As part of the project, she was given a privileged upbringing with access to the best education around, while at home being instilled with the world views of Dr. Oswell E. Spencer, Earl Spencer. Dr. Lord Spencer's ultimate goal was that these children would later be infected with a Progenitor Virus strain and usher in a Utopian superhuman society, and though the virus was not yet ready for this goal he recognised the need for the several hundred candidates to share their worldviews with himself. As a young-adult, Alex left her home into higher-level education in a field of her choosing, and was headhunted by Umbrella Pharmaceuticals as one of a short-list of as little as thirteen candidates. How many of the other Weskers Alex was raised with is unknown, though she was close to Albert, an Umbrella virologist, of whom the two were considered the best candidates of the project.
By the 1990s, Alex was mostly or even fully aware of Project Wesker, kept a secret to others, and was an acquaintance of Dr. Lord Spencer as a senior member of the Umbrella Intelligence Division. On the Umbrella CEO's instructions, in 1998 the Wesker candidates were infected with the prototype virus as part of the next phase in the project. Alex and Albert were the only confirmed survivors of this procedure, though Albert was able to fake his death for several months. The virus had a 20% probability of negligible mutation for each candidate, and became a certainty in Alex due to an incurable illness she had developed. Consequently, she possessed no superhuman powers. When confirming Albert's apparent death in August 1998, Alex strongly suggested replacing their losses by infecting the hundreds of washout candidates who, though not as academically successful still shared the same upbringing, but it appears this never game into fruition.
Alex herself was not as loyal to Dr. Lord Spencer as he believed, and made sure to use her position to build a power base of her own while Umbrella Pharmaceuticals still had resources she could use. On 19 July 2000, Alex and a team of Umbrella researchers, among whom her loyal confidant, Stuart, landed on Sushestvovanie Island. A small Russian island which suffered an economic collapse during the Fall of the Soviet Union, Alex chose to take advantage of their desperation before using them as guinea pigs. Using Umbrella's funds, Alex kickstarted an economic recovery by hiring the locals to construct a research complex. Seeking to eventually use the locals as guinea pigs, she also saw the re-opening of its mines, which made an ideal place for abducting test subjects. Unaware of this, she was hailed as a messianic figure by the locals for her actions.
After the final collapse of Umbrella in 2003, Alex remained at Dr. Lord Spencer's side. Sent out to Umbrella's old facility at Sonido de Tortuga Island, Alex was instructed to divert viral weapons research towards the creation of a virus which would halt the telomere-shortening properties of human cells which had made ageing an inevitability. To be infected with a such a mutagen would have made him biologically immortal. Already feeling the effects of her own degenerative illness, Alex gave up on the project and abandoned Sonido de Tortuga, taking all research data with her to Sushestvovanie Island, where she reformed it into the t-Phobos Project in 2006, a year after beginning the initial research. Instead of keeping alive an aged body, Alex's new project instead aimed at creating a virus which would allow memories and personality to be copied into a new body. This may have been brought on by her illness, as a new Alex would not suffer from a terminal disease. The problem in developing this virus, however, was that brain chemistry was the deciding factor in a successful transfer - production of hormones associated with fear would fail a candidate, and six months of exposure to the virus was necessary for Alex's copied consciousness to take over.
During work on t-Phobos, Alex received news firstly of Spencer's death in mid-2006, and secondly of Albert's death in early 2009. Though she had grown to see him as a feeble old man with delusions of grandeur, she appreciated his eugenics views and strove to see t-Phobos become a success, which would realise his dream but by making her the god of the new world instead. When she heard of Albert's death, she took a more personal blow, and as now the sole remaining of the thirteen candidates, she insisted the project be sped-up. Outside of t-Phobos, Alex also set-up the Kodoku Project, which aimed to create new bio-weaponry, being developed by loyal researchers within Umbrella's abandoned base on Sonido de Tortuga.
t-Phobos research had been tested on the wider population since 2008, largely by recruiting mine workers as a source of research and passing off their absence as them signing on to a full year's work. Alterations to the virus in January 2010 reduced the chances of killing the host and reducing the chance of them developing an immunity, but the test subjects to continue failing, having been overcome by their fears and turned into mutants rather than developing Alex's new life. Towards the end of the project, Alex separated herself from it, possibly due to her health, and moved on the duties of chief researcher to another, who worker with her and Stuart. With the virus finalised, though without any candidates, day-to-day work moved on to modifying the Uroboros Virus.
Running out of options, Alex began looking for new candidates from outside the island, and found her solution with Neil Fisher. Though the leader of the prominent NGO, TerraSave, Fisher had come to share the views of the incarcerated FBC leader Morgan Lansdale, that radical actions had to be taken to ensure global stability in the face of bioterrorism. The two agreed to a pact: he would supply members of his own organisation, who had experiences with facing mutants, in exchange for a sample of Uroboros so that a vaccine could be created, rendering it worthless as a black market product.
Some time in 2011, the operation began, with the abduction of over a dozen people at a company party, among whom Fisher himself as a means of obtaining Uroboros. One by one the pool was again met with failures, seeing the mutation of Gabriel Chavez when he attempted to escape the island in a booby-trapped helicopter while several others were killed by mutants, leaving only three remaining candidates: Claire Redfield, Moira Burton and Natalia Korda. Stuart's team continued monitoring the survivors' progress, and concluded Korda, a child, was the ideal candidate as childhood trauma made her incapable of feeling fear. Fisher was ordered therefore to abduct Korda and take her directly to Alex, so that she could be put in a comatose state for the next six months to ensure the experiment's success.
Seeking to tie-up loose ends, Alex infected Fisher with the modified Uroboros strain to turn him into a monster rather than simply handing it over. Stuart meanwhile oversaw the killing of all researchers ahead of his own suicide so that they not accidentally interfere with other plans. As Korda was placed into storage in a bunker beneath her tower, Alex was confronted by Redfield and Burton, the two remaining candidates who had also become unnecessary to her plans. Believing everything to be complete, Alex took out a handgun and shot herself in the head, which triggered the facility's self-destruct system.
Alex, however, did not die as planned. In her final moments between pulling the trigger and her intended death, she felt the fear of dying and becoming nothing. Her unconscious body began to quickly mutate, turning her into powerful and disfigured mutant, wearing robes and a mask to disguise her deformation. In the six-month wait for Korda's awakening, Alex fell into an existential crisis. She had once triumphed the project as effectively making her immortal, birthed into a new body, but was disturbed at the idea of two Alexes existing simultaneously. Korda therefore began to be seen as an impostor Alex, unworthy of holding the mantle of a god.
"I understand how you felt, Albert. It's not enough to live. I want to transcend!"
— Alex before transforming
When the weeks approached before Korda's awakening, Alex began planning her death, and released the Uroboros B.O.W.s, Revenants, onto the island with the goal of killing everything left. Alex found Korda outside the mines, escorted by BSAA supervisor Barry Burton. Knocking Burton off a cliff, she was free to do with Korda as she pleased. Infuriated that Korda showed no sign of the copied-consciousness, she declared her to be a failure and began choking her. With Korda close to passing out, something sparked in Alex's mind and she became fled before finishing the job. She confronted Korda and Burton again in the mines, where she infected herself with the modified Uroboros virus. Alex tried once more in trying to kill Korda, but was knocked to the ground by Moira, who had survived the past six months on the island as well. Chasing the three out to a cliff-edge, Alex's time ran short when faced with a BSAA assault on Sushestvovanie. With weapons supplied by the BSAA, Alex was killed by a rocket launcher before she could achieve vengeance.
Alex's legacy continued after her death, though not entirely as she had planned. The copied consciousness by July 2013 achieved a success in Korda, who became intrigued by the writings of Franz Kafka and newspaper articles on bioterrorism. The following year, the Kodoku Project was completed, with the researchers offering themselves as test-subjects out of a cultlike devotion to Alex, though the Ultimate Bioweapon on Sondio de Tortugo was destroyed during a BSAA operation coinciding with an attempt by Sheng-ya Pharmaceutical to steal the research.
↑These files have been heavily altered to remove religious connotations. The Japanese versions explicitly describe her as the messiah (救世主様,Kyuuseisyu-sama?) and goddess (女神様,megami-sama?), respectively.