"Hey boys? Is that any way to treat a lady? "
— Alice Clone to Umbrella soldiers after the death of her counterpart.
The Alice clones are perfect recreations of the original Alice, retaining all of the original's physical and psionic abilities. They were specifically created to derive a strain of the t-Virus to reverse the ravenous effects of the original virus in the undead by increasing their intelligence.
In his research for a way to pacify the massive undead population swarming the globe, Dr. Sam Isaacs created a multitude of clones of Alice. Using their blood, Isaacs devised a serum that was supposed to increase the intelligence of zombie test subjects. However, while the serum did succeed in temporarily increasing the zombie's intelligence, it actually increased their ferocity and the strength of the infection.
The first clone seen in the film. She woke up in the bathtub, just as Alice did years before, wandering through a replica of the Spencer Mansion and The Hive. She survived the laser room, and made it all the way to the end of the test grid, a recreation of the hallways of Raccoon City hospital, where she was killed by a Bouncing Betty. Her body was dumped onto the surface.
Activated midway through the film, this clone also makes it all the way to the end of the testing grounds, only to be ambushed and killed by an Enhanced Zombie.
Woken during the fight between the original Alice and the mutated Dr. Isaacs, the clone apparently died in Alice's arms after being freed from suspended animation; She revived in time to deactivate the lasers in the testing ground after they slice Issacs to pieces, saving the real Alice seconds before they kill her too. The clone is present with Alice as the other clones begin to wake up from suspended animation.
Dozens of dead clones are also seen in a disposal ditch on the surface, near the entrance to the underground lab. When Alice discovers them, she appears to remember them as they died at the hands of the obstacles in the underground facility mock-up of Raccoon City Hospital. Presumably, there are eighty seven dead clones in all, as Clone #86 was the first activated and died, along with Clone #87.
In Resident Evil: Afterlife, Alice leads an army of clones into the Umbrella's underground facility in Tokyo. At least one of the clones in the film show the original Alice's physical and mental prowers, notably telekinesis. The group encounter an impressive force of soldiers, defeating them with little or no trouble despite their losses.
At least two clones are able to reach Wesker before they are killed. The final clone he executes manages to set off two grenades, setting the entire facility on high alert. The remaining clones are killed when Wesker blows up the Tokyo facility after he escapes, unaware that the real Alice is on board with him. None of the Alice clones survive the blast as the facility is completely destroyed.
As part of simulations with the T-Virus and Las Plagas parasite, in the Umbrella Prime facility, the Red Queen manufactured more clones of Alice which are part of the fifty basic models of people used for the simulations. According to Ada Wong, they only get a basic imprint of memory and are dropped into various situations with various jobs. Unlike the original clones of Alice, these don't seem to posses her powers.
Alice (Suburban Housewife)
Alice awoke disoriented in the home she shared with her husband, Carlos Olivera, and her daughter Becky. Already late to deliver her daughter to school, Alice's home was overrun by Plaga undead and her husband killed. She escaped with Becky to the streets where she was rescued by activist neighbor Rain Ocampo. A short time afterward their car was struck by a truck and overturned. They escaped into a nearby home and hid. Overwhelmed, Alice attacked and killed one of the undead only to be attacked and killed by an undead version of her husband.
A clone of Alice was active in the New York City simulation.
Hundreds of deactivated and unprogrammed clones were under under production at Umbrella Prime. They were destroyed by Alice.
- In Afterlife, the clones' footwear constantly alternates from high heels to flat-soled shoes.
- In a deleted scene for Extinction, the White Queen reports that one clone was killed in the laser tunnel; Dr. Isaacs suspects the intelligence in the clones worsens as they go on.