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Resident Evil: Operation Raccoon City is known for its purposely-anachronistic artistic style in regards to real-world objects. A common example of this is the featuring of firearms made as late as 2009, though can also include cars.
The M16A4 was first produced in 2004 (although a lookalike could be built because Picatinny rail AR-15 receivers were first developed in the early 80s).