Ashley Graham (アシュリー・グラハム,Ashurī Gurahamu?) is the daughter of former US President Graham. She was briefly held captive by the Spanish cult Los Iluminados as a means of gaining control over the Presidency.
After receiving intelligence about Ashley's whereabouts, the U.S. Government sends agent Leon S. Kennedy to investigate the area. He discovers that the local villagers are actually members of Los Iluminados, converted to their beliefs through parasitic organisms known as Las Plagas. Leon discovered Ashley in a church on the outskirts of the village. Shortly afterwards, the two met with the cult leader, Osmund Saddler, who revealed that Ashley (as well as Leon) was administered with one of the Plaga parasites, and that Saddler was planning to return Ashley to the President in order to infiltrate and destroy the U.S. Government from within.
After escaping Saddler and the villagers, the two found their way into Ramon Salazar's castle, and later, into Saddler's island complex. Ashley would repeatedly be recaptured by Los Iluminados during Leon's mission and subsequently rescued each time. Within the island complex, the two found a laser surgery machine built by Luis Sera with the purpose of removing a Plaga internally from its host's body. Leon and Ashley used the machine on themselves, destroying their Plaga parasites and thus, removing Saddler's only leverage on them.
After Saddler was eliminated, Leon and Ashley made their escape from the collapsing island on a jet ski left by Ada Wong. Ashley offered Leon to come over to her place for "some overtime", which Leon politely declined. Afterwards, the both of them were picked up by American authorities.
Excerpt from biohazard4 kaitaishinsho revised edition, p. 8: アメリカ合衆国大統領グラハムのひとり娘。20歳。マサチューセッツ州の大学に在籍しているが、学校から帰宅する途中、何者かの手で連れ去られた。ヨーロッパのとある村に監禁されていたところをレオンに救出され、彼と力を合わせて、ともに狂気の村からの説出をはかる。明るくサバサバとした性格で、初対面の者にも物怖じしない。お孃さまであるためか少々ワガママな態度が目につくが、過酷な状況に直面しても泣きごとを言わずに突破口を見つけようとする、けなげな娘である。
↑Biohazard 4 Kaitaishinsho Kaitei Ban. BradyGames. p. 8.