|This article does not cite any sources. (March 2022)|
Anderson opens by talking about his experience obsessively playing Resident Evil for a month, and pitching the idea of a film to fellow Impact Pictured producer Jeremy Bolt. In doing Afterlife, Anderson wanted to move the franchise into a new direction, comparing it to the shift in styles from The Terminator to Terminator 2: Judgment Day.
The Alice character has also gone through a reimagining for the film, with Milla Jovovich describing it as Alice finally seeing herself in the world. For the new trilogy, Anderson also felt she should lose her superhuman powers which were introduced at the end of Resident Evil: Apocalypse, as she could now be at risk from individual Undead once more.
Glen MacPherson describes Anderson's visual style for this film as loving wide-shot lenses, which made it difficult at times to properly light. Niven Howie returned as film editor, and talks about how editing took place in the same building as the soundstage, allowing them to edit the film quickly. At the end of the short, Anderson and Crompton talk about the implications of family life on the film, with the young Ever Gabo Anderson interrupting recordings by parotting the words "action" and "cut".