Colmillos (コルミロス,korumirosu?) are Plaga-infested wolves in Resident Evil 4. The name means "Fangs" in Spanish. They are notable in that each must see you before it will attack (though if a Plaga emerges, the Plaga itself will attack you).
Colmillos first appear if Leon attempts to re-cross the lake after slaying Del Lago. A pack of four of these creatures awaits him on the opposite shore. Later on, near the Church, a pack of 3 is encountered which must be dealt with in order to continue. Ramon Salazar also keeps around a dozen of these vicious creatures in his maze garden, calling them his pets, where they will attempt to ambush the player while exploring the Maze.