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Daniela Dimitrescu was a mutant human resident to Castle Dimitrescu, who lived in the castle with Alcina Dimitrescu and two other mutants whom she regarded as "sisters", Bela and Cassandra. Daniela is the youngest daughter and she is noted to be one of the craziest and most delusional of the three.
At some point during or prior to the 1950s, Daniela was 'created' by Alcina after her body was exposed to a mutant species of insect. The resulting effects gifted Daniela with a youthful appearance, the ability to dissipate into the insects at will, and a thirst for human blood. She and her sisters would often enact their sadistic tendencies on staff and visitors alike, having strict requirements about their living conditions and seemed to have a particular preference to blood from men.
When Ethan Winters wandered into Castle Dimitrescu looking for his daughter, Daniela and her sisters brought him before their mother with the intent to consume his flesh once Mother Miranda was informed of his capture. Ethan was able to escape and the three sisters then began to pursue him through the castle.
When Ethan walks intro the Library, Daniela lays in wait for him as the last remaining sister following the deaths of Bela and Cassandra and attacked him, commenting that he would also fall for her in time like the others. However, the Library's skylight could be opened and exposes her to the same cold that incapacitated her sisters. Though she had to be lured into the center of the room for it to be effective, her attempt to kill Ethan ultimately ended in failure and she disintegrated into dust, while crying out that she doesn't want to die
Daniela, along with her sisters, were mutant humans born from masses of an unknown species of mutant insects resembling blowfies. These flies are born through the Cadou laying its eggs on a host, though the insect themselves cannot reproduce. After being exposed to the host's flesh, the flies will consume it over the course of days and cover the body in the swarm. During this time, the flies begin to mimic the human form, capable of changing their colors create the desired look, similarly to a chameleon's chromatophore. In this way, the flies are capable of swarming or morphing themselves to form the likeness of a human, similarly to the Mimicry Marcus.
Being made out of the insects, Daniela is able to dissipate into the swarm at will in order to move around the castle at very high speeds. She is unable to be hurt in this state as the multitude of insects either absorb or deflect any attacks put towards her. However, the insects that make up Daniela's body are notably weak against sudden drops in temperature, especially below 10°C (50°F). Exposure to such cold causes a drastic decrease in metabolism, eventually resulting in dormant, cryptobiotic state which leaves them vulnerable to attacks from conventional weapons.
Daniela is primarily encountered in the Library of the castle, where she shares the same abilities as her sisters. She can inflict persistent damage from swarm she is a part of when she gets too close and can lunge towards Ethan and bite at his neck. She cannot be harmed normally unless Ethan opens the skylight, where her exposure to the cold severely weakens her strength. Unable to transform into the swarm, she resorts to instead using her sickle weapon in a mad frenzy to kill Ethan, but is able to be hurt by Ethan's arsenal like any other enemy.
- Daniela's character is inspired by the so-called "Brides of Dracula" in Bram Stoker's Dracula. These women are vampires who live with Count Dracula at his castle as part of his pseudo-family. In the novel they are eager to both seduce and consume Jonathan Harker and have to be silenced by the Count himself, who instead presents them with an infant for sustenance.
- When her face is covered, Daniela can be identified by her green pendant.