(In the original Resident Evil 2, the virus was known as the God Virus which is why the vaccine for it is known as Devil.) |
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| + | [[File:RE2_Birkin_2.png|thumb|right|Dr. William Birkin following Golgotha infection. The asymmetrical mutation, growth of a second head, new arms and eyeballs encapsulate the randomness of the mutations caused by infection.]] |
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| − | :{{Redirect-acronym|G|[[William Birkin]]}} |
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| + | The '''Golgotha Virus''', abbreviated as '''G-Virus''', is a retrovirus in the [[Progenitor]] family of viruses. Golgotha was developed by [[Umbrella USA]] as a bioweapon to rival and surpass [[Tyrant Virus]] ("t-Virus"). The two viruses, while being descended from Progenitor, are totally dissimilar. Whereas t-Virus typically causes minor mutations in human hosts, like Zombies and Tyrants, Golgotha causes such extreme genetic mutation victims are no longer recognisable as human.<ref name=":3">''biohazard archives'' (2nd ed.), p.300.</ref> Human t-Virus mutants are almost unanimously infertile, while Golgotha's "G" mutants are highly-fertile and asexually reproductive.<ref name=":3" /> t-Virus causes necrosis of the body as a side-effect, while Gologotha is capable of repairing dead cells, and even reviving the dead.<ref name=":3" /><ref>http://www.projectumbrella.net/articles/Yasuhisa-Kawamura-Interview-Project-Umbrella</ref> Because of these factors, the BSAA regards Golgotha as one of the greatest threats to the planet if an outbreak were to occur.<ref name=":4">[[BSAA Remote Desktop]], [[G-Virus report]].</ref> |
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| − | ''<nowiki/>'' |
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| − | [[File:G-Virus.png|thumb|right|The G-Virus, preserved within a purple liquid.]] |
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| − | The '''Golgotha Virus''', also known as the '''God Virus''' and often abbreviated as '''G-Virus''', is a genetically-engineered species of virus within the Progenitor family. While the t-Virus typically causes cellular necrosis in infected organisms, the G-Virus is able to repair dead cells and bring its host back to life, effectively granting biological immortality. The most extreme can be seen in humans, where the former infected become Zombies, suffering brain damage and deterioration of the skin and muscles. By comparison, G-Virus infected humans suffer no such effects, though an uncontrolled dose will cause rapid mutation to better adapt to the current environment and situation, a mutational process dubbed "evolution".<ref>[[BSAA Remote Desktop]], "[[G-Virus report]]".</ref> G-Virus research was led by Dr. William Birkin, who's ultimate goal was to use it for eugenics purposes, and create a race of augment humans dubbed "G-Humans".<ref>http://www.projectumbrella.net/articles/Yasuhisa-Kawamura-Interview-Project-Umbrella</ref> |
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==History== |
==History== |
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| − | G-Virus was first discovered in 1988 in the body of Lisa Trevor, a biological weapons test subject kept at Umbrella USA's top-secret [[Arklay Laboratory]]. Trevor had been injected with a variety of viral strains over a twenty year period and ever since her initial Progenitor Virus infection in 1967 had survived tests others had perished during. As Umbrella's bioweapons research entered its third stage, the development of highly-intelligent weapons, it reached an impasse. Umbrella USA's Tyrant Project found that a gene crucial in human mutation towards a powerful, intelligent form was extremely rare. Umbrella Europe, meanwhile, was devoted to the Nemesis Project and had an intelligent organism, the [[NE-α Type]] parasite, which would kill its host after five minutes of taking over its nervous system. Dr. William Birkin, then chief of research at the Arklay Laboratory, procured one of the prototypes and implanted it within Lisa's body. The parasite was killed by Lisa's body and its DNA absorbed into her genome. Searching for the cause of this spontaneous mutation, Dr. Birkin's team isolated the primitive G-Virus. Birkin theorised that a G-Virus infection could induce mutations within the human body more beneficial than the random mutations and zombification observed with the t-Virus. Dr. Oswell E. Spencer, himself an avid eugenicist, supported Birkin's research on the G-Virus despite it being unrelated to their bioweapons research, and invested construction in a new research facility beneath Raccoon City to support it. |
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| + | === G-Virus Project === |
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| − | As research neared completion in 1998, Dr. Birkin grew frustrated with the company who were unwilling to offer him a position as an executive. After observing footage of the Queen Leech in July, both he and his former colleague, [[Albert Wesker|Dr. Albert Wesker]], made the decision to leave Umbrella altogether. Over the summer, Birkin made contact with the US military and reached an agreement to provide them with the G-Virus for their own bioweapons project. Umbrella's headquarters was tipped off by their own moles within the US military and prepared an Umbrella Security Service operation to retrieve it first. Though their recovery was a success and [[Christine Henry]] received her promised sample, the company suffered a significant loss. Nearly the entire G-Virus research team died in the chaos, as a group of Hunters were released from confinement to coincide with the team's arrival. Nearly the entire G-Virus research staff was killed in various ways, and Birkin infected himself with a sample of the virus to prevent death from a gunshot wound, soon after killing most of the USS team in a rampage and releasing the t-Virus into the sewer ecosystem, itself moving to the water supply. By the night of September 30 only Birkin's wife, Dr. Annette Birkin, was alive in Raccoon City and did her best to keep the facility defended from spies, encountering Ada Wong who was sent from a rival company to hunt down any remaining samples and was eventually successful. Dr. Annette Birkin also instructed civilian Claire Redfield with how to develop the DEVIL antigen, after learning Annette's daughter Sherry was implanted with one of her husband's embryos. |
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| + | Golgotha was isolated in 1988 by Dr. [[William Birkin]], the chief researcher at Umbrella USA's top-secret Arklay Laboratory. Found in the body of Lisa Trevor, a human test subject, its discovery was made following her immune system's inexplicable destruction of an [[NE-α Type]] parasite,<ref>''Wesker's Report II'', Part 4.</ref> and could theoretically have existed since the late 1960s when testing on her began.<ref>''Wesker's Report II'', Part 1.</ref> As Golgotha was determined to be able to genetically alter a living being repeatedly and unpredictably as well as be able to repair damaged cells and revive the dead, it ran counter to Umbrella's plans to create reliable military-grade B.O.W.s that could be controlled by Army trainers. [[Umbrella Pharmaceuticals]]' CEO, Dr. [[Oswell E. Spencer, Earl Spencer]], was nonetheless interested in Golgotha for its potential eugenics purposes, and authorised development as an R&D project unrelated to the [[t-Virus Project]].<ref>''biohazard archives'' (2nd ed.)</ref><ref group="excerpt">Excerpt from biohazard archives (2nd ed.): "「G」 発見のきっかけを作ったのは、 後にネメシス計画の中心となる寄生生物「NE-''α''型」 の原型である。 これを、 驚異的な生命間で生き続けていた生体サンプル、 リサ・トレヴァーに移植したところ、 脳へ寄生する間もなく消滅。 ウィリアムがリサを詳しく調べた結果、 彼女の体内で新たに覚醒したと思われるG-ウィルスの原型が確認された。 この画期的発見は、 t-ウィルス計画を逸脱するものであり、 ウィリアム自身も即座に本部へ「G-ウィルス計画」 を立案して承認を得た。 これにより、 アンブレラはラクーンシティの地下に巨大研究施設を建造し、 ウィリアムはそこを拠点に新になウィルス開発を始めることになる。<br />G-ウィルスがtーウィルスと本に違う点は、 感染した生体自身がまったく新しい生命体に進化を遂げるところにある。 t-ウィルスは一世代だけの突然変異体（ミュタント）を生み出すに過ぎないが、 G-ウィルスは繁な「G生物」 を生み出す力を持っている。 つまり、 ウィルスによってもたらされたG細胞が、 生態の構造を組み替えながら肉体を侵食。 これによって感染者は予測不可能な劇的進化を繰り返し、 子孫を増やす能力を持つ人工種となるわけである。 G-ウィルスには、 この他にも死人を蘇らせる特性もあるという。 それだけに、 G-ウィルスはt-ウィルスを超える恐るべき発明として認識しておく必悪がある。<br />しかし、 その未知なるウィルスの開発は、 ウィリアムのエゴイズムによって結論を見ないまま幕を閉じる。 米国政府（軍部） 側へ寝返ることを考えていた彼は、 スペンサーに自分の研究を横取りされることを拒絶し、 すべてを独占しようと企んだのだ。 これに業を煮やしたアンブレラは、 特殊工作部隊を使ってサンプルの強奪に乗り出すが、 ウィリアムが自分自身にG-ウィルスを投与したために事態は急変。 ウィリアムは、 G-ウィルスによる ”人間の進化” を、 自分の肉体を使ってまざまざと見せ付けた。"</ref><ref name=":2">''Wesker's Report II'', Part 5.</ref> Early research on Golgotha took place in France at an underground research complex led by Dr. [[Christine Henry]], a French countess from a family connected to Dr. Spencer.<ref>BIO HAZARD 2 DRAMA ALBUM ~The Female Spy Ada Lives~~</ref> This partnership ceased in 1991 with the completion of NEST within a limestone cavern in the outskirts of Raccoon City.<ref name=":2" /> |
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| − | Following the 1998 Raccoon City incident, the G-Virus fell into the possession of four parties: Umbrella Europe, the rival company; a scientist later going by the name of Frederic Downing, the sole escapee of the Raccoon City laboratory, and the United States government, who had placed Sherry Birkin into protective custody as a means of extracting samples. |
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| + | The G-Virus Project reached its final stages in 1998 alongside the t-Virus Project which Dr. Birkin also oversaw. Through the abduction of locals, the NEST researchers were able to get their hands on a number of test subjects for both projects, including children at a nearby orphanage. The accelerated use of test subjects was, in fact, so high that the newly-commissioned [[Incineration Disposal Plant P-12A]] suffered a biohazard due to having to process too much biowaste. As the months drew on, Dr. Birkin became increasingly frustrated with Umbrella's board of executives, with both becoming increasingly suspicious the other would seize the completed virus for themselves. He entered secret negotiations with the US military, instead, expecting to earn protection as a new addition to their own bio-weapons project. When Umbrella HQ's moles within the US military reported back on this new development, an [[Umbrella Security Service]] team was sent out to detain Dr. Birkin for crimes against Umbrella and seize the virus to complete its research under Dr. Henry in France.<ref>''[[Op Instructions]]''.</ref> |
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| − | Umbrella Europe continued study the G-Virus, but the only known result of their research was the t+G Virus, a t-Virus strain that mutated from exposure to G-antibodies. Dr. Downing took up a top research position in WilPharma and, in 2005, provided both the t-Virus and the G-Virus to Dr. Curtis Miller, a virologist who was radicalised and convinced by Downing to commit terrorist attacks in Harvardville. Miller transformed after G-Virus infection, leading to the destruction of WilPharma's laboratory, enabling Downing to fake his death and escape with his samples in the hopes of selling to the [[Republic of Bajirib]], a state-sponsor of bioweapons. Of the American research, Derek C. Simmons was able to provide The Family with a sample from Sherry Birkin, which was used in the creation of the C-Virus which would be used in attacks across the globe from 2011 to 2013. |
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| + | On the night of 22 September, the USS made its attack on NEST and fatally wounded Dr. Birkin in their recovery. In his dying actions, he infected himself with a remaining sample of Golgotha and mutated into a powerful [[G]] mutant that massacred the security team, and leaked both Golgotha and the [[Tyrant Virus]] into the sewers. As Raccoon City soon fell to a t-Virus outbreak, Dr. Birkin continued to wander around, seeking people to implant with [[G-embryo]]s to propagate his new species. How many [[G]]s were created is uncertain, though it is known some corpses were also infected with the virus and became [[G-Zombie]]s. Further attempts to steal Golgotha continued during the outbreak. Within NEST itself, Dr. Monica and a man later known as Dr. Frederic Downing both tried to escape Raccoon City with samples. In Dr. Monica's case she stole an embryo from an pre-final G test, and was killed by it during her escape attempt. In Dr. Downing's case, he succeeded in escaping with a virus sample, either from the finalised version or a near-finalised, and tried to make a new life for himself outside Raccoon City. The US Army made an attempt to recover the virus in the form of [[Delta Force]], and used Umbrella's private subway system to get to the lab and retrieve it; unfortunately for them they took the wrong route and were killed at the P-12A plant. Umbrella's own attempt to retrieve Golgotha succeeded in the early hours of 30 September, when Alpha Team leader "HUNK" recovered a sample and got in touch with an Umbrella helicopter. |
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| − | To the BSAA, the G-Virus represented one of the greatest threats to mankind, and in the event of use in bioterrorism the local branch had orders to contain it immediately. In the event the outbreak spread further, the BSAA contingency plan was for the deployment of all BSAA agents around the world. |
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| + | In the early hours of 30 September, Dr. Birkin parasitised his daughter, [[Sherry Birkin|Sherry]], which led to her being rushed to NEST to be treated with the DEVIL vaccine on the advice of Dr. Birkin's wife, Dr. [[Annette Birkin]], by then the only surviving NEST still in the city. This vaccine was designed to halt mutations caused by the virus,<ref name=":1">''Resident Evil 2'' (1998), file: "[[Vaccine synthesis]]".</ref> but as a vaccine could not reverse mutation, the recommended procedure was an emergency surgery to remove G-cells in the body. This did not take place due to the severity of the outbreak, made worse by the facility undergoing a self-destruct and Annette's death. At the same time, the facility was infiltrated by Ada Wong, an agent for a rival company sent to retrieve a sample of Golgotha. Wong ultimately failed to retrieve a sample, though escaped with a skin tissue sample taken from Dr. Birkin. Dr. Birkin was himself killed attempting to escape NEST in an underground train, though accounts differ as to if he was killed by the train self-destructing or being consumed by the explosion from NEST. |
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| − | As with its [[t-Virus]], Umbrella considered the G-Virus' primary means of infection to be through injections. To date, only two individuals have been witnessed undergoing primary infection: Dr. [[William Birkin]] and [[Curtis Miller]]. Unlike creatures created by the t-Virus, "G"s cannot pass infection on to other creatures through physical contact and injury (e.g. bites and open wounds). |
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| − | The secondary infection is drastically different, and relates to the "G"s' reproductive system. If a "G" decides upon using a human as a breeding tool, they will turn the individual into a host for its embryo through oral implantation with its reproductive organ, seen on William to be on his hand. |
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| + | Further research and modification of the Golgotha Virus took place in the years after Raccoon City, with Umbrella Europe, the rival company, Dr. Downing and the US military all succeeding in retrieving samples, the latter through placing Sherry Birkin in government custody as a means of both studying her G-cells and keeping her away from those seeking the virus. |
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| + | Umbrella Europe used Golgotha in research on marrying the G- and t- Projects, in what became known as the t+G Virus. This virus was for the most part a t-Virus mutated from exposure within a hostile environment of G-antibodies, possibly within a G itself. The virus went through at least two iterations as research continued, and all known samples were stolen in September 2002 by terrorist Dr. Morpheus D. Duvall, and later destroyed with the destruction of a missile silo he had based himself in as well as a cruise ship he used to get there. |
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| + | Golgotha was used by Dr. Downing in late 2005 as part of a black market bioweapons sales pitch to the Republic of Bajirib. Having radicalised Dr. Curtis Miller into using viral weapons as a means of politicing debate on them and revealing the US military's previous involvement with Umbrella USA, Dr. Downing sought to use footage of t-Virus outbreaks caused by Dr. Miller, as well as his own infection with Golgotha, as proof of concept. Bajirib was interested in both viruses, despite Dr. Downing's own recommendation against Golgotha, though the sale failed when USSTRATCOM was able to track him down and detain him. |
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| − | Should the host be of a complementary genetic makeup to the parasite - generally through identical blood groups, as with William and his daughter, [[Sherry Birkin|Sherry]] - then a bond between the two will form, leading to the host's assimilation by the parasite, and subsequent mutation into a creature perhaps comparable to the first "G". To date, this occurrence has not been recorded as having happened due to the rarity of G-Virus usage. The only successfully implanted host with a DNA match - Sherry Birkin - was saved from assimilation by the experimental [[G-Vaccine]], codenamed DEVIL, before mutation could occur, with help from her mother, [[Annette Birkin|Annette]], and [[Claire Redfield]]. |
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| + | Though the US military made no known attempts to create bioweapons after Raccoon City, [[The Family]], an American exceptionalist movement with strong ties to the government and civil service, initiated the C-Virus Project on its behalf as a private endeavour, believing the US would inevitably return to developing bio-weapons and not wanting rival countries like China to advance beyond it in the meantime. Through access to Sherry, who herself had been confirmed to possess regenerative and anti-ageing abilities, The Family was able to obtain G-Cells from her body as well as any Golgotha virions being produced. By splicing G cells into a sample of t-Veronica obtained in 2002, the [[Chrysalid virus|Chrysalid Virus]] was able to cause extreme mutations in humans as well as revive the dead. |
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| − | Alternatively, a host whose DNA is incompatible will reject the parasite in a matter of minutes. The embryo rapidly grows inside its host before bursting from their chest. Upon exiting the host body, the embryo quickly mutates into its adult form. [[Brian Irons]], police chief of the [[Raccoon City Police Department]], [[Ben Bertolucci]], a journalist attempting to investigate Chief Irons, and [[Monica]] are the only known victims to suffer this rejection of a G-embryo after being infected by William Birkin. |
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| + | The BSAA has so far never been forced to combat a Golgotha outbreak. Nonetheless, their official policy is that if the virus is detected, the entire BSAA force is to be put on alert should the local branch be inadequate to destroying all trace, with that point being determined by the creation of new G-humans.<ref name=":0">[[BSAA Remote Desktop]], "[[G-Virus report]]".</ref> |
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| − | As shown by its creator, William Birkin, the G-Virus is capable of revitalizing the body of its host. However, the host becomes mutated into a monstrous creation that loses any human memories, becoming driven by only instinct. Signs of G-Virus infection indicate an increase in muscle mass of the host with mutated sections of flesh over the upper body, an enlarged third eye on the shoulder, and extended claws on a single hand. |
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| − | The G-Virus grants its host increased strength, durability, vitality, and strong abilities of regeneration. Also, the G-Virus is capable of cellular mutations to the body should it sustain severe injuries, allowing it to mutate into more powerful form to adapt to various conditions. Even with the G-Vaccine, the virus can still change to the body, retaining the regenerative factor. |
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| + | [[File:G-Virus.png|thumb|right|The G-Virus, preserved within a purple liquid.]]There are two significant manners by which Golgotha is able to transmit between individuals. The first is injection of the virus into the body. Umbrella USA's NEST facility kept a number of vials of Golgotha in storage, preserved within a protein media dyed purple for immediate identification. As the incubation period for Golgotha is very short, injection of a full or near full vial as performed by Dr. William Birkin is known to bring about mutation within seconds, though it is possible this process would be delayed if a smaller dosage is injected. |
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| + | The second manner of transmission is by implantation by which of a G-embryo. These organisms are the natural offspring of G-mutants, and are forced into a human host's body via oral implantation. By being host to the parasitic embryo, the victim is then at risk of being infected from within. If the host is of a close genetic relationship to the embryo's parent, there is a high probability the embryo will merge into the host's body and mutate them into Gs themselves.<ref name=":5">''Resident Evil: The Darkside Chronicles'' (2010), file: "[[G-Virus Antigen]]".</ref> If the host is not deemed compatible, the embryo will force its way out within minutes, killing the host. It is uncertain if a rejected host will be infected with the virus. |
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| − | However, there is only so much damage that the body can take before it becomes destabilized, leaving the G-virus only to regenerate and evolve what remains. |
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| − | The G-Virus is also capable of reanimating dead bodies, creating "[[G-Zombie]]s".<ref>http://projectumbrella.net/articles/RESEARCH-BIOHAZARD-2-final-edition</ref><ref>http://projectumbrella.net/articles/Zombies-File</ref><ref>Resident Evil 2'' (1998), dialogue with Annette: "''The G-Virus is able to revive the dead".</ref> |
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| + | Golgotha has extreme effects on the human body. The virus infects cells close-by, turning them into so-called "G-Cells". These G-Cells then produce more of the virus, which will spread further across the body. As this gradual spread starts from the point of infection, the body may mutate asymmetrically. This is seen in Dr. Birkin, who infected himself in the right arm, which became considerably muscular in comparison to the left.<ref>Official Guide Book, p.53.</ref> |
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| + | Golgotha's extreme mutations are not stopped simply from the creation of G-Cells. If part of the body is injured, it will regenerate. This ultimately causes the host's DNA to be re-written, leading to significant changes in the body during the regeneration. In the case of Dr. Birkin, he is known to have grown an entirely new head, with the original, human, head being moved down to the chest.<ref>Official Guide Book, p.54.</ref> Other noticeable aspects of the extreme mutations were the growth of a second pair of arms, which later mutated further into feet, and the re-shaping of the rib-cage into a mouth with bone teeth.<ref>''Official Guide Book'', p.56.</ref> |
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| − | ==Microbiology== |
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| − | A primitive form of the virus was discovered in the mutated body of [[Lisa Trevor]], on whom the Umbrella Corporation had been conducting unethical genetic and viral experiments for three decades. When she displayed unexpected immune resistance to the experimental [[NE-α Type]] parasite, Birkin and other researchers looked for a cause and found what would later become the G-Virus. The virus was subsequently developed by [[Umbrella Corporation]] scientist [[William Birkin]], who had also claimed credit for [[James Marcus]]' work on the [[t-virus]]. |
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| + | <nowiki> </nowiki>Outside of Dr. Birkin's unique mutation, two common elements are known to occur within most G-mutants. The first is that of eyeballs which are known to develop in seemingly random parts of the body for no particular reason. This is comparable with [[Wikipedia:Teratoma|teratomas]], a type of tumour which grows hair, teeth and eyes. The second is that of asexual reproduction, the manner of which is uncertain.<ref name=":5" /> Dr. Birkin was capable of reproducing embryos soon after infection, though was not seen doing so for another seven days, while second-generation "G" were capable of giving birth to embryos within minutes of their own birth. In both types of mutations, the individuals gave birth via the mouth. This may be typical with G, or simply the result of the embryos sharing random traits developed in Birkin's body. As observed in Raccoon City, third-generation G - effectively Birkin's grandchildren - were incapable of maturing past their larval stage exposing a generational defect in G mutants.<ref name=":4" /> |
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| + | There are, further-more, two other occurrences of G mutants which do not fit other examples. The first is that of the G-Zombies, human corpses infected with the G-Virus in some manner (e.g. embryonic implantation within a corpse or, perhaps, the revival of rejected hosts). These creatures are not 'true' G, and remain genetically human, albeit with their body turned pink from the G-Cells. The second anomaly is that of Sherry Birkin. This individual is the only known instance of a host being genetically compatible with the embryo, but was vaccinated during a short window after implantation and, consequently, did not develop extreme mutations aside from regenerative abilities. Whether or not she possesses any other traits is unknown. |
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==Treatment== |
==Treatment== |
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| + | {{See also|DEVIL}} |
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| − | Alongside work on the G-Virus, Drs. William and Annette Birkin also devised the DEVIL vaccine to suppress the virus' take-over of the body. However, as the vaccine could only be injected into an infectee who still had not succumbed to the virus, its only realistic usage would be the administration of hosts - particularly hosts genetically similar to the "G". When Sherry Birkin was vaccinated, some aspects of the virus was preserved within her DNA. In the same vein as [[Lisa Trevor]], Sherry developed extraordinary regenerative abilities, though nowhere near what she could have been capable of if left unvaccinated. |
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| + | A treatment for Golgotha was devised by the NEST research team while working on the virus itself. Codenamed "DEVIL", this vaccine was recommended for use by NEST staff in the event of an outbreak, and had a high success rate in preventing the virus from infecting a patient's cells. This vaccine can be used on a patient who has already been infected with the virus, though the window for success is short and varies from host to host.<ref name=":5" /> Further mutations beyond this point prevent the vaccine from working at all.<ref name=":5" /> As the vaccine cannot reverse mutation, those vaccinated after infection will show some mutation but cease mutating further.<ref name=":1" /> NEST's scientists devised a form of surgery to remove growths of G-Cells in the body. As G-Cells naturally produce the virus, their removal is necessary to wiping the virus from the body. |
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| ⚫ | *The localization for ''Resident Evil 2'' erroneously inferred that the [[T-00]] (referred to as "that monster that is tearing apart the precinct") was created by the G-Virus and that it was the ultimate bioweapon when Brian Irons was explaining its properties to Claire. In the original script, he instead commented that the virus has the ability to rapidly advance human evolution without even mentioning the T-00. |
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==Gallery== |
==Gallery== |
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G ORC Hunk-bmp.jpg|G-Virus sample landing near HUNK in Operation Raccoon City |
G ORC Hunk-bmp.jpg|G-Virus sample landing near HUNK in Operation Raccoon City |
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</gallery> |
</gallery> |
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| ⚫ | *The localization for ''Resident Evil 2'' erroneously inferred that the [[T-00]] (referred to as "that monster that is tearing apart the precinct") was created by the G-Virus and that it was the ultimate bioweapon when Brian Irons was explaining its properties to Claire. In the original script, he instead commented that the virus has the ability to rapidly advance human evolution without even mentioning the T-00. |
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| + | ==Bibliography== |
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| + | *{{cite book|title=[[BIOHAZARD 2 Official Guide Book]]|editor=Tahara, Seiji (田原 誠司)|publisher=[[Famitsu]] |location=Japan|year=1998}} |
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| + | *{{Cite book|title=[[Resident Evil Archives: Umbrella's Virus Uncovered]]|publisher= BradyGames|page=|pages=|isbn=0744006554|date=9 November 2005|others = Translated by Zpang America, Inc.|editor1-surname = Sumner|editor2-surname = Shotten|editor3-surname = Owen|editor1-first = Christian|editor2-first = Brian|editor3-first = Michael}} |
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==Sources== |
==Sources== |
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| + | ;excerpts |
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| + | <references group="excerpt" /> |
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<references /> |
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{{Mutagens}} |
{{Mutagens}} |
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{{Resident Evil 2 lore}} |
{{Resident Evil 2 lore}} |
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{{Resident Evil: Degeneration lore}} |
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[[Category:Resident Evil 2 lore]] |
[[Category:Resident Evil 2 lore]] |
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Revision as of 07:47, 12 December 2019
(Capcom's primary storyline)
Dr. William Birkin following Golgotha infection. The asymmetrical mutation, growth of a second head, new arms and eyeballs encapsulate the randomness of the mutations caused by infection.
The Golgotha Virus, abbreviated as G-Virus, is a retrovirus in the Progenitor family of viruses. Golgotha was developed by Umbrella USA as a bioweapon to rival and surpass Tyrant Virus ("t-Virus"). The two viruses, while being descended from Progenitor, are totally dissimilar. Whereas t-Virus typically causes minor mutations in human hosts, like Zombies and Tyrants, Golgotha causes such extreme genetic mutation victims are no longer recognisable as human.[1] Human t-Virus mutants are almost unanimously infertile, while Golgotha's "G" mutants are highly-fertile and asexually reproductive.[1] t-Virus causes necrosis of the body as a side-effect, while Gologotha is capable of repairing dead cells, and even reviving the dead.[1][2] Because of these factors, the BSAA regards Golgotha as one of the greatest threats to the planet if an outbreak were to occur.[3]
History
G-Virus Project
Golgotha was isolated in 1988 by Dr. William Birkin, the chief researcher at Umbrella USA's top-secret Arklay Laboratory. Found in the body of Lisa Trevor, a human test subject, its discovery was made following her immune system's inexplicable destruction of an NE-α Type parasite,[4] and could theoretically have existed since the late 1960s when testing on her began.[5] As Golgotha was determined to be able to genetically alter a living being repeatedly and unpredictably as well as be able to repair damaged cells and revive the dead, it ran counter to Umbrella's plans to create reliable military-grade B.O.W.s that could be controlled by Army trainers. Umbrella Pharmaceuticals' CEO, Dr. Oswell E. Spencer, Earl Spencer, was nonetheless interested in Golgotha for its potential eugenics purposes, and authorised development as an R&D project unrelated to the t-Virus Project.[6][excerpt 1][7] Early research on Golgotha took place in France at an underground research complex led by Dr. Christine Henry, a French countess from a family connected to Dr. Spencer.[8] This partnership ceased in 1991 with the completion of NEST within a limestone cavern in the outskirts of Raccoon City.[7]
The G-Virus Project reached its final stages in 1998 alongside the t-Virus Project which Dr. Birkin also oversaw. Through the abduction of locals, the NEST researchers were able to get their hands on a number of test subjects for both projects, including children at a nearby orphanage. The accelerated use of test subjects was, in fact, so high that the newly-commissioned Incineration Disposal Plant P-12A suffered a biohazard due to having to process too much biowaste. As the months drew on, Dr. Birkin became increasingly frustrated with Umbrella's board of executives, with both becoming increasingly suspicious the other would seize the completed virus for themselves. He entered secret negotiations with the US military, instead, expecting to earn protection as a new addition to their own bio-weapons project. When Umbrella HQ's moles within the US military reported back on this new development, an Umbrella Security Service team was sent out to detain Dr. Birkin for crimes against Umbrella and seize the virus to complete its research under Dr. Henry in France.[9]
On the night of 22 September, the USS made its attack on NEST and fatally wounded Dr. Birkin in their recovery. In his dying actions, he infected himself with a remaining sample of Golgotha and mutated into a powerful G mutant that massacred the security team, and leaked both Golgotha and the Tyrant Virus into the sewers. As Raccoon City soon fell to a t-Virus outbreak, Dr. Birkin continued to wander around, seeking people to implant with G-embryos to propagate his new species. How many Gs were created is uncertain, though it is known some corpses were also infected with the virus and became G-Zombies. Further attempts to steal Golgotha continued during the outbreak. Within NEST itself, Dr. Monica and a man later known as Dr. Frederic Downing both tried to escape Raccoon City with samples. In Dr. Monica's case she stole an embryo from an pre-final G test, and was killed by it during her escape attempt. In Dr. Downing's case, he succeeded in escaping with a virus sample, either from the finalised version or a near-finalised, and tried to make a new life for himself outside Raccoon City. The US Army made an attempt to recover the virus in the form of Delta Force, and used Umbrella's private subway system to get to the lab and retrieve it; unfortunately for them they took the wrong route and were killed at the P-12A plant. Umbrella's own attempt to retrieve Golgotha succeeded in the early hours of 30 September, when Alpha Team leader "HUNK" recovered a sample and got in touch with an Umbrella helicopter.
In the early hours of 30 September, Dr. Birkin parasitised his daughter, Sherry, which led to her being rushed to NEST to be treated with the DEVIL vaccine on the advice of Dr. Birkin's wife, Dr. Annette Birkin, by then the only surviving NEST still in the city. This vaccine was designed to halt mutations caused by the virus,[10] but as a vaccine could not reverse mutation, the recommended procedure was an emergency surgery to remove G-cells in the body. This did not take place due to the severity of the outbreak, made worse by the facility undergoing a self-destruct and Annette's death. At the same time, the facility was infiltrated by Ada Wong, an agent for a rival company sent to retrieve a sample of Golgotha. Wong ultimately failed to retrieve a sample, though escaped with a skin tissue sample taken from Dr. Birkin. Dr. Birkin was himself killed attempting to escape NEST in an underground train, though accounts differ as to if he was killed by the train self-destructing or being consumed by the explosion from NEST.
Post-Raccoon City
Further research and modification of the Golgotha Virus took place in the years after Raccoon City, with Umbrella Europe, the rival company, Dr. Downing and the US military all succeeding in retrieving samples, the latter through placing Sherry Birkin in government custody as a means of both studying her G-cells and keeping her away from those seeking the virus.
Umbrella Europe used Golgotha in research on marrying the G- and t- Projects, in what became known as the t+G Virus. This virus was for the most part a t-Virus mutated from exposure within a hostile environment of G-antibodies, possibly within a G itself. The virus went through at least two iterations as research continued, and all known samples were stolen in September 2002 by terrorist Dr. Morpheus D. Duvall, and later destroyed with the destruction of a missile silo he had based himself in as well as a cruise ship he used to get there.
Golgotha was used by Dr. Downing in late 2005 as part of a black market bioweapons sales pitch to the Republic of Bajirib. Having radicalised Dr. Curtis Miller into using viral weapons as a means of politicing debate on them and revealing the US military's previous involvement with Umbrella USA, Dr. Downing sought to use footage of t-Virus outbreaks caused by Dr. Miller, as well as his own infection with Golgotha, as proof of concept. Bajirib was interested in both viruses, despite Dr. Downing's own recommendation against Golgotha, though the sale failed when USSTRATCOM was able to track him down and detain him.
Though the US military made no known attempts to create bioweapons after Raccoon City, The Family, an American exceptionalist movement with strong ties to the government and civil service, initiated the C-Virus Project on its behalf as a private endeavour, believing the US would inevitably return to developing bio-weapons and not wanting rival countries like China to advance beyond it in the meantime. Through access to Sherry, who herself had been confirmed to possess regenerative and anti-ageing abilities, The Family was able to obtain G-Cells from her body as well as any Golgotha virions being produced. By splicing G cells into a sample of t-Veronica obtained in 2002, the Chrysalid Virus was able to cause extreme mutations in humans as well as revive the dead.
The BSAA has so far never been forced to combat a Golgotha outbreak. Nonetheless, their official policy is that if the virus is detected, the entire BSAA force is to be put on alert should the local branch be inadequate to destroying all trace, with that point being determined by the creation of new G-humans.[11]
Transmission
The G-Virus, preserved within a purple liquid.
There are two significant manners by which Golgotha is able to transmit between individuals. The first is injection of the virus into the body. Umbrella USA's NEST facility kept a number of vials of Golgotha in storage, preserved within a protein media dyed purple for immediate identification. As the incubation period for Golgotha is very short, injection of a full or near full vial as performed by Dr. William Birkin is known to bring about mutation within seconds, though it is possible this process would be delayed if a smaller dosage is injected.
The second manner of transmission is by implantation by which of a G-embryo. These organisms are the natural offspring of G-mutants, and are forced into a human host's body via oral implantation. By being host to the parasitic embryo, the victim is then at risk of being infected from within. If the host is of a close genetic relationship to the embryo's parent, there is a high probability the embryo will merge into the host's body and mutate them into Gs themselves.[12] If the host is not deemed compatible, the embryo will force its way out within minutes, killing the host. It is uncertain if a rejected host will be infected with the virus.
Effects
- See also: William Birkin, Curtis Miller, G, and G-Zombie
A third eye on some part of the body (typically the shoulder) was a common feature of creatures imbued with the G-virus.
Golgotha has extreme effects on the human body. The virus infects cells close-by, turning them into so-called "G-Cells". These G-Cells then produce more of the virus, which will spread further across the body. As this gradual spread starts from the point of infection, the body may mutate asymmetrically. This is seen in Dr. Birkin, who infected himself in the right arm, which became considerably muscular in comparison to the left.[13]
Golgotha's extreme mutations are not stopped simply from the creation of G-Cells. If part of the body is injured, it will regenerate. This ultimately causes the host's DNA to be re-written, leading to significant changes in the body during the regeneration. In the case of Dr. Birkin, he is known to have grown an entirely new head, with the original, human, head being moved down to the chest.[14] Other noticeable aspects of the extreme mutations were the growth of a second pair of arms, which later mutated further into feet, and the re-shaping of the rib-cage into a mouth with bone teeth.[15]
Outside of Dr. Birkin's unique mutation, two common elements are known to occur within most G-mutants. The first is that of eyeballs which are known to develop in seemingly random parts of the body for no particular reason. This is comparable with teratomas, a type of tumour which grows hair, teeth and eyes. The second is that of asexual reproduction, the manner of which is uncertain.[12] Dr. Birkin was capable of reproducing embryos soon after infection, though was not seen doing so for another seven days, while second-generation "G" were capable of giving birth to embryos within minutes of their own birth. In both types of mutations, the individuals gave birth via the mouth. This may be typical with G, or simply the result of the embryos sharing random traits developed in Birkin's body. As observed in Raccoon City, third-generation G - effectively Birkin's grandchildren - were incapable of maturing past their larval stage exposing a generational defect in G mutants.[3]
There are, further-more, two other occurrences of G mutants which do not fit other examples. The first is that of the G-Zombies, human corpses infected with the G-Virus in some manner (e.g. embryonic implantation within a corpse or, perhaps, the revival of rejected hosts). These creatures are not 'true' G, and remain genetically human, albeit with their body turned pink from the G-Cells. The second anomaly is that of Sherry Birkin. This individual is the only known instance of a host being genetically compatible with the embryo, but was vaccinated during a short window after implantation and, consequently, did not develop extreme mutations aside from regenerative abilities. Whether or not she possesses any other traits is unknown.
Treatment
- See also: DEVIL
A treatment for Golgotha was devised by the NEST research team while working on the virus itself. Codenamed "DEVIL", this vaccine was recommended for use by NEST staff in the event of an outbreak, and had a high success rate in preventing the virus from infecting a patient's cells. This vaccine can be used on a patient who has already been infected with the virus, though the window for success is short and varies from host to host.[12] Further mutations beyond this point prevent the vaccine from working at all.[12] As the vaccine cannot reverse mutation, those vaccinated after infection will show some mutation but cease mutating further.[10] NEST's scientists devised a form of surgery to remove growths of G-Cells in the body. As G-Cells naturally produce the virus, their removal is necessary to wiping the virus from the body.
Gallery
Further notes
- The localization for Resident Evil 2 erroneously inferred that the T-00 (referred to as "that monster that is tearing apart the precinct") was created by the G-Virus and that it was the ultimate bioweapon when Brian Irons was explaining its properties to Claire. In the original script, he instead commented that the virus has the ability to rapidly advance human evolution without even mentioning the T-00.
Bibliography
- Tahara, Seiji (田原 誠司), ed (1998). BIOHAZARD 2 Official Guide Book. Japan: Famitsu.
- Sumner, Christian; Shotten, Brian; Owen, Michael, eds (9 November 2005). Resident Evil Archives: Umbrella's Virus Uncovered. Translated by Zpang America, Inc.. BradyGames. ISBN 0744006554.
Sources
- excerpts
- ↑ Excerpt from biohazard archives (2nd ed.): "「G」 発見のきっかけを作ったのは、 後にネメシス計画の中心となる寄生生物「NE-α型」 の原型である。 これを、 驚異的な生命間で生き続けていた生体サンプル、 リサ・トレヴァーに移植したところ、 脳へ寄生する間もなく消滅。 ウィリアムがリサを詳しく調べた結果、 彼女の体内で新たに覚醒したと思われるG-ウィルスの原型が確認された。 この画期的発見は、 t-ウィルス計画を逸脱するものであり、 ウィリアム自身も即座に本部へ「G-ウィルス計画」 を立案して承認を得た。 これにより、 アンブレラはラクーンシティの地下に巨大研究施設を建造し、 ウィリアムはそこを拠点に新になウィルス開発を始めることになる。
G-ウィルスがtーウィルスと本に違う点は、 感染した生体自身がまったく新しい生命体に進化を遂げるところにある。 t-ウィルスは一世代だけの突然変異体（ミュタント）を生み出すに過ぎないが、 G-ウィルスは繁な「G生物」 を生み出す力を持っている。 つまり、 ウィルスによってもたらされたG細胞が、 生態の構造を組み替えながら肉体を侵食。 これによって感染者は予測不可能な劇的進化を繰り返し、 子孫を増やす能力を持つ人工種となるわけである。 G-ウィルスには、 この他にも死人を蘇らせる特性もあるという。 それだけに、 G-ウィルスはt-ウィルスを超える恐るべき発明として認識しておく必悪がある。
しかし、 その未知なるウィルスの開発は、 ウィリアムのエゴイズムによって結論を見ないまま幕を閉じる。 米国政府（軍部） 側へ寝返ることを考えていた彼は、 スペンサーに自分の研究を横取りされることを拒絶し、 すべてを独占しようと企んだのだ。 これに業を煮やしたアンブレラは、 特殊工作部隊を使ってサンプルの強奪に乗り出すが、 ウィリアムが自分自身にG-ウィルスを投与したために事態は急変。 ウィリアムは、 G-ウィルスによる ”人間の進化” を、 自分の肉体を使ってまざまざと見せ付けた。"
- references
- ↑ 1.0 1.1 1.2 biohazard archives (2nd ed.), p.300.
- ↑ http://www.projectumbrella.net/articles/Yasuhisa-Kawamura-Interview-Project-Umbrella
- ↑ 3.0 3.1 BSAA Remote Desktop, G-Virus report.
- ↑ Wesker's Report II, Part 4.
- ↑ Wesker's Report II, Part 1.
- ↑ biohazard archives (2nd ed.)
- ↑ 7.0 7.1 Wesker's Report II, Part 5.
- ↑ BIO HAZARD 2 DRAMA ALBUM ~The Female Spy Ada Lives~~
- ↑ Op Instructions.
- ↑ 10.0 10.1 Resident Evil 2 (1998), file: "Vaccine synthesis".
- ↑ BSAA Remote Desktop, "G-Virus report".
- ↑ 12.0 12.1 12.2 12.3 Resident Evil: The Darkside Chronicles (2010), file: "G-Virus Antigen".
- ↑ Official Guide Book, p.53.
- ↑ Official Guide Book, p.54.
- ↑ Official Guide Book, p.56.
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