(Covers information from Anderson's universe)
When the t-virus was unleashed into the city, Henderson and the other S.T.A.R.S. members tried to keep the chaos under control.
Their numbers were severely curtailed after the police force, along with the Umbrella Biohazard Countermeasure Service, engaged in a failed campaign to suppress the Undead. Along with his remaining officers, Henderson retreated to the Westwood Theatre. They were discovered by the Nemesis, who slaughtered them under the order of Timothy Cain.