The Iron Maidens (アイアンメイデン,aian-meiden?) were a species of human bio-weapon created by Los Iluminados. They were derived from the earlier Regenerador species.
Iron Maidens were produced on a Spanish island controlled by Los Iluminados. They were part of the wider research into the abilities of the Plaga parasites in human hosts and the viability of Plaga-based bio-weapons, of which Dr. Luis Sera was a major contributor for. All known Iron Maidens are believed to have been killed during the 2004 abduction of the First Daughter, Ashley Graham, which led to US involvement in the region.