(Capcom's primary storyline)
"I’m not like my siblings. I want nothing more than to be free of that bitch. So I need power. I need enough power to destroy her. These are the fruits of my power. The strong will destroy the weak, that’s the way of the world.
— Karl Heisenberg
Lord Karl Heisenberg was a human mutant who lived in an Eastern European mountain range. A genius in engineering, he is assumedly the patriarch of the Heisenberg family. He runs the inherited Heisenberg Factory, located just outside the village, and serves Mother Miranda, along with the other three major houses in the mountain range.
Heisenberg was one of the children who was kidnapped and subjected to the Cadou parasite experiments by Mother Miranda, who brainwashed him into being her servant. Eventually, he, Alcina Dimitrescu, Donna Beneviento, and Salvatore Moreau became Miranda's lieutenants.
Among the Lords of the Four Houses, Heisenberg was the only one who held a grudge against Miranda, due to her own selfish desire to revive her late daughter and how he saw Miranda's family as nothing more than experiments. As such, he secretly planned a rebellion, hoping to use Rose's latent powers to defeat Miranda. At one point, he attempted to persuade Ethan to join him, but the latter refused upon Heisenberg revealing his plan to weaponize Rose.
The Heisenberg family was closely associated with the noble Beneviento, Moreau, and Dimitrescu families, and maintained an alliance with them in controlling the region. This control allowed the Heisenberg family to run their factory with barbarous cruelty, and according to sources, Heisenberg rarely strayed from it, preferring to hole himself up in its walls.
First Confrontation with Ethan
Heisenberg first met Ethan as he ventured to Castle Dimitrescu, encountering him in a chamber before the Castle. He noted that Ethan was an outsider, and that Mother Miranda would like him, before impaling him with a metal bar and encasing him in scrap metal.
Afterwards, Heisenberg dragged Ethan to a meeting with Miranda and the other Lords. At one point, he told Angie and Moreau to stop talking before belittling Lady Dimitrescu and making his case to Miranda to decide Ethan's fate. He won out, but Dimitrescu protested, to which he responded by insulting her further before Miranda called for silence. He proceeded to put on a show for the Lords, forcing Ethan to run through the mines and evade an ever-increasing number of Lycans, before finally subjecting him to a large grinder to kill him with. However, Ethan escaped unharmed.
Second Confrontation with Ethan
Almost a full day later, after Dimitrescu, Beneviento and Moreau have been killed by Ethan, Heisenberg contacted him through a television screen two times, once to direct him to his flask, containing a piece of Rose, and again to lead Ethan to his factory.
When Ethan discovered Heisenberg's wall covered with crossed-out pictures of the other Lords and Mia, Heisenberg made his presence known to him and told him to sit down. After forcing him to comply, he revealed to Winters that Miranda had been using him to kill each of the House Lords one by one with the intention to replace them as Miranda's sole enforcer. Knowing that he was the next intended fight, Heisenberg instead proposed that they work together to kill Miranda using the revived Rose. When Ethan refused, Heisenberg dropped him into the lower depths of the factory to be killed by the Sturm and his other experiments.
Mutation and death
Despite Heisenberg’s hopes that Ethan would no longer bother him, he came back and exited the factory through the use of the machine that Heisenberg had created and Chris Redfield prepaired and entrusted to him. Angered that he continued to challenge him, but willing to fight him nonetheless, the two engaged in combat, with Heisenberg mutating inside the metal apparatus he had created to becoming a massive cybernetic creature. Throughout the battle, Heisenberg continually taunted Ethan, prematurely claiming victory and ridiculing his attempts to kill him multiple times.
The battle continued until the explosives that Chris had planted detonated inside the factory, destroying it entirely and all the machines that lay within. Outraged at the loss of his army and factory, Heisenberg continued to fight Ethan with vigor until he created a whirlwind of metal, lifting him into the air and attempting to kill him one last time. However, Ethan managed to grab on to the machine Chris had given him in midair and launched its full arsenal at Heisenberg, damaging his apparatus beyond repair. Distraught, Heisenberg once more proclaimed his need to kill Miranda, after which he exploded and calcified.
- ↑ Resident Evil Village (2021), file: "Diary".
- ↑ Resident Evil Village - Ending Credits