The Loop (Games)
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- Spencer, Ozwell E. - CEO of Umbrella Pharmaceuticals. Co-discoverer of Progenitor Virus (deceased).
- Ashford, Edward - Co-founder of Umbrella Pharmaceuticals (deceased).
- Marucs, James - Co-founder of Umbrella Pharmaceuticals; co-discoverer of Progenitor Virus (deceased).
- Vladimir, Sergei - Head of Russian Branch, head of Red Umbrella (deceased)
- Ashford, Alexander - Researcher (deceased)
- Ashford, Alexia - Chief Researcher of Antarctic facility, created T-Veronica virus, discovered "ancient virus" (deceased)
- Birkin, William - Chief Researcher, created "G" (deceased)
- Wesker, Albert - Researcher, created the Uroboros Virus in 2008 (defected\deceased)
- Unnamed Umbrella Officer - Possibly head of Umbrella's operations in Raccoon City
- Bailey, Brandon - Chief Researcher and Research Center Director of Umbrella Africa Research Center (deceased)
- Goldman, Vincent - Head of Research Center in Sheena Island (deceased)
- Henri, Christine - Research and Development Head Manager of French Branch, head of Blue Umbrella
- Klein - Designed Hypnos, created its special gene (deceased)
- Dr. Cameron - Created the gene therapy, accidentally discovered T-Cameron Virus (4D Executer)
- Ashford, Alfred - Head of Rockfort Island (deceased)
- Unnamed Umbrella Researcher - Possibly involved in the creations of the Bandersnatch and the Albinoid (deceased)
- Unnamed Umbrella Researcher (Outbreak) - Involved in the creations of the Hunter series (deceased)
- Duvall, Morpheus D. - Researcher (defected\deceased)
- Suzuki, Yoko - Researcher (former)
- Monica - Researcher (deceased)
- Rodriguez - Commander in the USS 2nd Squad (defected)
Executive and Administration
- Tommy Neilson - Executive
- Resident Evil (2002), file: "Security Protocols"
- Wesker's Report II.
- Emergency report
- Resident Evil (1996), file: "Eric's Letter".
- Resident Evil (2002), file: "Keeper's Diary"
- Resident Evil (2000), file: "Keeper's Diary".
- Resident Evil (2000), file: "Researcher's Will".
- Resident Evil (2002), file: "Suicide Note".
- Resident Evil (2002), file: "Security Protocols".
- Resident Evil (2002), file: "Plant 42 Report"
- Resident Evil (2002), Keeper's Diary
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