Resident Evil Wiki
Resident Evil Wiki
Prime universe
(Capcom's primary storyline)
Further notes

"I choose... to die a human!"
— Manuela, before attempting to let herself get killed.[2]

Manuela Hidalgo (b.c.1986) is a Superhuman of Latin American heritage. The daughter of drug lord Javier Hidalgo, Manuela was a recipient of an experimental viral therapy treatment using t-Veronica Virus to treat a degenerative condition, something which was only accomplished by his financial influence. Following an intentional leak of t-Virus in and around Amparo, Manuela became the sole survivor and was kept in US federal protection due to the severe risk of her being abducted by black market bioweapons developers.


Early life[]

Hidalgo was born and raised in the isolated Amparo region lying within the Amazon Rainforest. Through her mother, Hilda, she inherited a degenerative condition which greatly risked her quality of life. At the age of 5, her mother was taken away for experimental "t" viral therapy; suffering from runaway mutations as a result of improper procedure,[3] Hilda was kept in captivity and Hidalgo told her mother was dead. For the rest of her childhood, Hidalgo was spoilt by her father, who wanted her to want for nothing, but was to remain at their private estate under the protection of the Sacred Snakes cartel.[4]

In 2001, at the age of 15, Manuela was diagnosed with the same degenerative disease her mother had.[5] Faced with a rapid deterioration, her father used his underworld connections to obtain t-Veronica from an organisation affiliated with Dr. Albert Wesker. The viral therapy showed promise, but like t-Virus, improper use was a risk. Based on data provided, the spread of the virus had to be artificially slowed down over a period of 15 years, at which point Hidalgo's condition was expected to stabilise. Without access to the necessary antiretroviral drugs or cryonic technology, the Sacred Snakes instead began abducting teenage girls from nearby Mixcóatl to be harvested for organ transplants.

2002 Amparo raid[]

"I don't want to live if it means others have to die."

In 2002, Manuela discovered the nature of her therapy and the sacrifice to keep her alive. Disgusted with herself and afraid of her father, she fled downriver to seep shelter in Mixcóatl. Her safety was short-lived however, and after realising where she had gone her father released the water from the nearby hydro-electric dam, flooding the village. Immediately after this, t-Virus infected prisoners were released into the area and began massacring the locals, spreading Cannibal Disease to the survivors. Soon, Hidalgo was left alone.

4584929243 e87ceb1120 o-1-

Manuela awakening on a boat

Around this time, American agent Leon S. Kennedy and his special forces accomplice Jack Krauser entered the village, on a mission to arrest Javier for his dealings in the black market. The two found Manuela in a church singing to her mother, though she was unaware of who it was at the time. Her mother was stopped from killing her by Manuela's singing, which allowed Hilda's mind to gain control briefly. After fighting off Hilda, the two sought aid from Manuela in finding Javier. Although unaware of her connection to the criminal, the villagers knew a lot of him. Their guide killed before their arrival, the two employed Manuela as their unofficial replacement.

Reaching the interior of the dam, Manuela was separated from Leon and Krauser when Javier managed to get her back. The two Americans were swept away into the inner-workings of the dam by the rapids. They would find Manuela while attempting to get through a flood door after she escaped from her father. By this time, they realized that she was Javier's daughter. Leon began to suspect that she had been infected with the t-Veronica virus, though Manuela would resist answering until after they reached the road above the dam.

4584941283 2152752c6a o-1-

Manuela realizing that the monster is her mother

Reaching the mansion, Manuela discovered the corpses of the doctors who treated her, and came to the conclusion that Javier had them shot after her first escape. Further into the mansion's underground, they discovered the corpse of one of the missing girls. Leon realized that it was the organ transplants from them that kept Manuela from degenerating. Javier again tried to take back Manuela, but was interrupted by Hilda, who began to attack the two Americans. Cornering and close to killing them, she was stopped by Manuela, who began singing to her again. Weak from the lack of transplants, she was unable to sing any more and Hilda's mind was defeated by her aggressive, animalistic persona. Manuela was saved again by the two agents, who stopped Hilda from reaching her daughter. It was only after her death that Manuela finally found out what the creature was.

Escaping the mansion and awaiting a rescue chopper, they were unexpectedly attacked by a new monster also derived from the t-Veronica virus. It was Javier, himself. Manuela realized that the only way to defeat her father was to use her blood which, due to the virus, combusted upon exposure to the Earth's Nitrogen/Oxygen atmosphere.

4584945721 d837598a7c o-1-

Manuela protecting Leon with her burning blood

Burning the joints of the monster, Javier suffered too much damage for his mind to keep in control. His last request was for his death, which Leon and Krauser granted.

The helicopter arrived just in time, and Manuela was treated for her wounds before being taken into the custody of the government, no changes were observed from her and she remained the same.

However, if the player takes too long to defeat Javier, Manuela loses too much blood and disintegrates into the sunset, but not before thanking Leon for rescuing her.


  1. Stated to be 5 years old in 1991.
  2. Resident Evil: The Darkside Chronicles (2009), scene: "Stake".
  3. Resident Evil: The Darkside Chronicles (2009), file: "Javier's Memorandum (1991)".
  4. Resident Evil: The Darkside Chronicles (2009), file: "Manuela Hidalgo".
  5. Resident Evil: The Darkside Chronicles (2009), scene: "Operation Javier 4 opening".
  6. Resident Evil: The Darkside Chronicles (2009), scene: "Distress".