The Nyx is an extremely tough B.O.W. and is very hard to kill even when using magnums and rocket launchers. Often it needs to be defeated by using the indestructible Combat Knife when the player has expended all his/her ammo. It's recommended to use Cindy Lennox for this tactic due to her ability to dodge every attack. Nyx is also capable of absorbing any unlucky survivor should they be in its way, causing the virus gauge to rapidly fill as though the survivor is incapacitated. This will likely involve the survivor getting killed, as it is unknown (And so far impossible) if you are able to escape it without your teammates killing it before the gauge fills. However, while being absorbed, you can still access your inventory, and it is possible to prolong how long you can endure it by using health items or the Anti-Virus to stop virus progression to buy yourself time, especially noteworthy on Showdown 3 , due to the fact that Nyx is not the final boss of that scenario. Nyx's weak point is actually its heart which will open after the monster has suffered much damage. Using the magnum to inflict damage on the creature's heart will kill it in five to six shots.