Unlike its successors, the T-001's spinal column was exposed when the t-Virus' negative effects causing "exfoliation" of the cells immediately behind it,[1][excerpt 1] leaving it extremely vulnerable to small-arms fire from behind.
Furthermore, its nervous system was far more primitive than its successors, leading to the T-001's somewhat-primitive behavior; poor coordination and random twitching. These were among the reasons why it was scheduled for disposal.