The Queen Plaga was a large plant-like organism which was the "mother" of the Plaga.
History
The Queen Plaga was an organism based in a castle tower. It was important to Los Iluminados, and it was here where new Plaga parasites were produced.[excerpt 1] In preparation for Ashley Graham's indoctrination into the cult, a ritual was performed here under the watch of Castellan Ramon Salazar.
In a desperate decision to kill Leon S. Kennedy, Salazar allowed himself and his remaining Verdugo bodyguard to be assimilated into the organism. However, the new chimera failed in its attack on Leon and all three constituent parts perished.