(Capcom's primary storyline)
The Queen Semiramis was a luxury cruise liner operated by the Paraguas Line Company. It was a carbon-copy of its sister ship, the Queen Zenobia. When Paraguas faced financial problems owing to the accessibility of airline flights to the public, both ships were sent out to be scrapped. However, the ships were taken control of by Il Veltro and were used in 2004 as a base of operations for their bio-weapons attack on Terragrigia. The BSAA Agent Chris Redfield alongside Jessica Sherawat, boarded the vessel in an attempt to rescue Jill Valentine and Parker Luciani, under the belief that it was the Queen Zenobia. The Semiramis was destroyed by its self-destruct sequence.