A remastered, high-definition version of the game has been released in January 2016, known in Japan as the biohazard 0 HD remaster (バイオハザード0 HDリマスター?). It was also included in the Origins Collection. A port of the remaster was released on May 21, 2019, for the Nintendo Switch.
Faced with the relentless Zombies and other horrifying creatures, S.T.A.R.S. officer Rebecca Chambers makes an alliance with Billy Coen, an escaped criminal. Unknowingly, Rebecca stumbles into the prelude of an event where she will be tested to her limits and her greatest fears will be realised. Together, Billy and Rebecca must survive the nightmare and expose the dark secrets of what has caused it.
Rebecca Chambers - An 18-year-old and university chemistry graduate, serving as the rookie medic for the S.T.A.R.S. Bravo Team. Chambers is on her first mission, which is to investigate the mysterious murders plaguing the Arklay Mountains. Soon after landing, the mission changes to focus on the apprehension of 2LT. Billy Coen. She is separated from her team in the search, and finds herself on the Ecliptic Express, a private Umbrella train which has mysteriously stopped in the forest.
Billy Coen - A dishonourably-discharged Marine officer of the rank of Second Lieutenant. Scapegoated for the massacre of civilians in a failed mission, Coen was being transported to a military base on the other side of Arklay County for his execution. His transport was destroyed and his MPs killed in an attack by an unknown force, forcing Coen to seek safety on the same nearby train.
Dr. James Marcus - An accomplished virologist and one of the three founding members of Umbrella Pharmaceuticals. Dr. Marcus led his own t-Virus research distinct from those of his fellows in the laboratory below Umbrella's executive training centre. He mysteriously disappeared ten years before the events of the game. A mysterious individual is now using infected leeches to coordinate attacks on Umbrella in his name.
Dr. William Birkin - An Umbrella researcher with an influential role in the t-Virus and G-Virus Projects. Dr. Birkin was one of the leaders in the project to re-open Dr. Marcus' training centre, when their teams were attacked by leeches.
Dr. Albert Wesker - An Umbrella security officer, former researcher, and Captain of the S.T.A.R.S. Alpha Team. Dr. Wesker has been assigned to oversee the re-opening of the training centre alongside Dr. Birkin.
Captain Enrico Marini - Bravo Team's leader. Captain Marini led the search for 2LT. Coen, and when Chambers was separated attempted to remain in radio contact.
Edward Dewey - The Bravo Team pilot. Dewey is attacked by dogs in the forest and escapes onto the Ecliptic Express soon after Chambers' arrival.
Bravo Team members Forest Speyer, Kevin Dooley, Dr. Kenneth J. Sullivan, and Richard Aiken also make appearances in-game; however, they have no dialogue and only serve a minor role. The only other reference to them as Bravo Team, is that they all head offscreen to Spencer Mansion a few miles away from the training school.
Completing the main game in any difficulty level will unlock Wesker Mode, allowing you to play the game as Albert Wesker who has two new abilities, as well as the bonus minigame Leech Hunter.