The Hong Kong company Tinhangse Publishing published a five-part Resident Evil 0 adaptation alongside the game. The plot has almost no similarity to the game, such as including vampires and Lisa Trevor.
A novelization of the game titled Resident Evil: Zero Hour was written by author S.D. Perry. It was the seventh book of the Resident Evil series but preceded all the other books in terms of chronological order. A prequel to the very first game (Resident Evil) or book (Resident Evil: The Umbrella Conspiracy), the main characters include the Bravo Team's Rebecca Chambers and an ex-Marine named Billy Coen.