The original TV trailer for BIOHAZARD 2 was directed by American horror movie director George A. Romero, who popularised the Zombie Horror genre in the 1960s. A live-action commercial featuring Leon S. Kennedy and Claire Redfield encountering Zombies in the Raccoon Police Station, the trailer was only available for advertisement in Japan due to copyright issues.
A series of shorts were also commissioned to advertise the DualShock re-release in Japan. They would introduce the audience to a typical setting in what is assumed to be Raccoon City - a gym; greasy spoon or construction yard - and then introduce a Zombie employee or customer.
BIOHAZARD 2 Value Plus, the Dreamcast port of the game, was given limited advertising space on Fuji TV and ABC in December 1999.
Two albums containing music from the game were released in January and August 1998, respectively. The first, BIOHAZARD 2 ORIGINAL SOUNDTRACK, is the main release and includes most of the significant compositions. The second, BIOHAZARD 2 COMPLETE TRACK, largely encompasses less prevalent themes but offers an orchestral medley and a second CD with sound effects and voice collections, as well as an interview with the sound staff.BIOHAZARD 2 ORIGINAL SOUNDTRACK received an identical European CD titled Resident Evil 2 Original Soundtrack. In the North American album of the same name, the opening theme "The Beginning Of Story" is split up into four individual tracks. Five orchestral arrangements of the game's music were included on the Bio Hazard Orchestra Album, a recording of a live concert performed by the New Japan Philharmonic. Disc jockey Piston Nishizawa created electronic remixes for several of the compositions, which were later released as the album Biohazard 2 Remix: Metamorphoses.