Resident Evil 5: Gold Edition has received criticism in the media of Islamic countries since its release in 2010. The focus of this criticism is in regards to accusations that the Holy Qur'an, the central text in Islam, appears in a disrespectful scene in the game.
Background
A book displaying Arabic-style artwork on its front cover is used in several places in "Lost in Nightmares". While it can easily be mistaken for the Qur'an, the lack of Arabic (or indeed English) writing identifying it as the Holy Qur'an leaves this intention unlikely.