"An easy to handle shotgun. It uses 12 gauge rounds."
— Item description.
The Shotgun E is a weapon that appears exclusively in Resident Evil Outbreak File #2.
The Shotgun E appears in the first three scenarios of File #2 ("Wild things", "Underbelly" and "Flashback"). The Shotgun E offers a weaker firepower and a slower reload than the Shotgun, but firepower remains consistent at longer ranges, whereas the Shotgun's ranged damage diminshes. Ammunition is readily available, even when choosing harder difficulties. The Shotgun E is extremely effective for defending against/defeating larger, more resilient foes, such as zombified lions, the zombified elephant and enlarged mega bites.