Star-Crossed Duo is an Action-Type card featured in Resident Evil: The Deck Building Game expansion set #1: Alliance. When played, this card is attached to a player's partner character if there is one. When exploring, assuming that the partner character is leading with this card attached, one of the player's partner's weapons get an additional 10 damage. This card also bestows +2cards, and an additional buy; the card has a cost of 40 gold to purchase.

The image shown on the card depicts Claire and Leon when starting Memories of a Lost City in Resident Evil: The Darkside Chronicles.

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