(Covers information from Anderson's universe)
Umbrella Prime is a top secret underground laboratory in Resident Evil: Retribution, under the command of the reprogrammed Red Queen.
Background
Located off the coast of northern Russia in submarine pens built in the 1980s, the facility was utilized for the testing of bio weapons (which would be too risky to test out in the real world) in a controlled environment; many potential purchasers could witness the viruses' destructive power. The submarines were used to transport the cargo around the world, with the unintended effect of causing the apocalypse of zombies and other mutations destroying all normal life.
The outpost had several replicated environments established inside of it, including reasonable facsimiles of several city blocks in New York, Moscow, Tokyo, and at the center was a replica of Raccoon City's suburbs. Among its other notable features was a massive cloning chamber that could produce hundreds of clones from the fifty available models and numerous bio-weapons. It was eventually flooded by Leon Kennedy's strike team while rescuing Alice.
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