Below is a list of all unlockables in the Resident Evil 2 remake.
|Preview||Mode||How to unlock|
|Leon [2nd]||Unlocked by completing Claire's [1st] scenario.|
|Claire [2nd]||Unlocked by completing Leon's [1st] scenario.|
|The 4th Survivor||Unlocked by completing any [2nd run] scenario or by purchasing the "All In-game Rewards Unlock" DLC.|
|The Tofu Survivor||Unlocked by completing The 4th Survivor or by purchasing the "All In-game Rewards Unlock" DLC.|
|No Way Out||Unlocked by completing No Time To Mourn, Runaway and Forgotten Soldier on any difficulty.|
∞ Bonus Weapons
- All of these weapons have infinite ammo, the unlockable Combat Knife never breaks, and it can be used to counterattack an enemy, but if done so it will be lost if the player doesn't collect it back by killing the enemy and examining its corpse.
- All ∞ Bonus Weapons will be unlocked at once if the "All In-game Rewards Unlock" DLC is bought.
Once unlocked, these weapons will be in the Item Box for both characters in every difficulty.
|Preview||Weapon name||How to unlock|
|Samurai Edge (Original Model)||Beat the game on Standard or Hardcore mode with an S rank.|
|Combat Knife||Destroy all Mr. Raccoons in the main game.|
|LE 5||Beat the game on Hardcore mode with an S rank.|
|ATM-4||Beat one of Leon's scenarios on Hardcore mode with an S+ rank.|
|Minigun||Beat one of Claire's scenarios on Hardcore mode with an S+ rank.|
These are the rank requirements according to the "Results" menu in-game.
- Using any ∞ Bonus Weapons except for the Combat Knife (Bonus Weapon) will negate an S+ rank.
- In order to get an S+ rank, you can only save 3 times maximum.
|STANDARD||Leon & Claire||
|STANDARD||Leon & Claire [2nd]||
|HARDCORE||Leon & Claire||
|HARDCORE||Leon & Claire [2nd]||
The Tofu Survivor
In The Tofu Survivor, four additional characters can be unlocked, all of them feature unique voices and a pre-determined loadout.
|Preview||Character||How to unlock||Notes|
|Konjac||Complete The Tofu Survivor once.||Loadout:
|Uiro-Mochi||Complete The Tofu Survivor once.||Loadout:
|Flan||Complete The Tofu Survivor with either Konjac or Uiro-Mochi.||Loadout:
|Annin Tofu||Complete The Tofu Survivor with either Konjac or Uiro-Mochi.||Loadout:
The following items can be unlocked in The Ghost Survivors mode:
|Preview||Accessory||How to unlock|
|Skull||Make a grenade by combining items.|
|Crocodile||Complete the Runaway scenario. (No training mode)|
|Gas Mask||Complete the Forgotten Soldier scenario. (No training mode)|
|Egghead||Complete and open all locks in the Runaway scenario. (No training mode)|
|Unicorn||Complete the Runaway scenario.|
|Mr. Raccoon||Destroy all Mr. Raccoons hidden in The Ghost Survivors mode.|
|Molded||Complete the No Way Out scenario.|
|G||Complete the No Time to Mourn scenario.|
|Ivy||Complete the Forgotten Soldier scenario.|
|Tyrant||Complete the No Time to Mourn scenario with both routes. (No training mode)|
|Licker||Complete the No Way Out scenario. (No training mode)|
|Tiger||Play The Ghost Survivors 3 times.|
|Sheep||Complete the No Time to Mourn scenario. (No training mode)|
|Raccoon||Play The Ghost Survivors 10 times.|
|Cat Ears (∞ ammo)||Complete the No Way Out scenario without firing more than 60 handgun shots. (No training mode)|