The following details unlockables in Resident Evil 4. This is content players do not initially have access to.
This does not include items hidden on stages nor the weapons you can get from the Merchant when he updates his shop as the player progresses through the main game.
During the main game
These can be found even during the first playthrough of the main game.
The player can obtain an early and free Punisher handgun by shooting 10 Blue Medallions and then talking to the Merchant. If all 15 are shot, the Punisher will be free and will include one firepower tune up.
These are cutscenes players are not assured to trigger while playing. These do not include special enemy death scenes triggered by their attacks or by running out of time during any countdowns.
|Chapter 1-1||Footpath to the village||Attempting to walk down the bridge near the starting point.||The police officers will tell you to stop.|
|Checking the cliff after the bridge is taken down.||Leon will look down the cliff.|
|Village centre||Walking into the two floor house while the villagers are attacking.||Leon will barricade himself inside the house and look out the window to notice the ganados planning something.||Leon has moved a dresser in front of the door, ladders are put up on the house, a Chainsaw Ganado spawns.|
|Chapter 1-3||Village chief's house||Walk back into the room where you found the Insignia Key.||Mendez will attack Leon again and Ada will fire at him from the window.||The window is now broken.|
|Church||Walk down the right path past the church instead of checking the door first.||Hannigan will call Leon and ask what he is doing.|
|Walk up to and examine the church door.||Hannigan will call Leon and he will explain that the door is locked.|
|Lake||Walk up the hill to the overview of the lake.||Leon sees the Del Lago eat one of the police officers.|
|Chapter 2-1||Go back to where the player first entered the area.||Leon will notice Colmillos howling.||Two Colmillos will spawn.|
|Quarry||Leon must help the dog out of the bear trap in the first chapter.||The dog will appear on a cliff and jump down.||The dog will assist Leon during the fight against El Gigante.|
|Chapter 2-2||Besieged hut||Shoot at Luis multiple times.||Luis will get angry at Leon and shoot him.||Instant death.|
|Chapter 3-2||Temple||Fire a rocket at the group of Cultists before they are alerted.||Scene will show the rocket hitting them all.||Most or all of the Cultists will die.|
|Castle parlour||Fail to stop the red robed cultist from running away.||The cultist will unveil a mounted turret.||The cultist will now be on the turret and shooting at the player.|
|Chapter 4-1||Dance hall||Shoot the big nest attached to the ceiling.||The nest will fall down.||A few different eye gems will be on the ground.|
|Chapter 5-1||Wharf A||Proceeding to the encampment without shooting out the light||The spotlight shines on Leon and an alarm blares||Enemies will be alerted to Leon's location.|
|Killing all the enemies in the base before proceeding||Enemies will push a boulder down at Leon||Instant death (if the quick time event is failed).|
|Communications tower||Check the controls.||Leon will try to call for help and backup.|
|Chapter 5-3||Prophet's room||Check Saddler's throne.||Leon will sit on the throne and relax.||Nothing happens, but does place the player in perfect view of the Elegant Headdress attached to the wall.|
|Final Chapter||Underground water vein||Turn around and walk to where Leon entered from.||Rocks will fall from the ceiling blocking the exit.|
The default title screen is a still image of Leon and Ashley. After beating the game once, the screen will change to a scrolling panoramic image of the village centre. The joystick can be pushed to change the scroll speed and direction of the image. After beating the game, there is no way to change the image back to the default one.
Players can restart the game after a completion with all their current equipment. The Merchant will also always have his full list of items and tune ups on sale as well as any extra weapons the player has unlocked.
Unlocked by beating the game once on normal mode, players now have the option of starting a new game (not a new round) on this difficulty setting. This serves as the game's hardest mode. Enemies take and deal more damage and most ganados do not hesitate to attack.
Extra weapons are only usable in completed game files.
|Matilda||Beat the main game once.|
|Infinite Launcher||Beat the main game once.|
|Handcannon||Obtain a 5 star rank with all characters on all stages in the Mercenaries minigame.|
|Chicago Typewriter||Clearing the Assignment Ada mini-game unlocks this for the maingame in the Gamecube version, but unlocks it for Separate Ways in all other versions. Beating Separate Ways will then unlock it for the main game.|
|P.R.L. 412||Beat Professional mode. This weapon is not in the Gamecube version.|
There are two sets of unlockable costumes. Players are given the option to select them when starting a new game or round. When selected, all costumes change based on the set, there is no option to change each character's costume individually or during mid game.
If the player has kept the tactical vest and chooses the "Default" costume set, Leon will have the vest on and not his jacket.
Set "Special 1" is unlocked by completing the game.
Leon will appear in an R.P.D. uniform. This is an updated version of his outfit from Resident Evil 2. Ashley will appear in a white and red-trimmed pop star outfit. Ada wears black combat gear. It also has the butterfly icon on her shoulder that is also present on her default dress. This is the same costume she wears during the Assignment Ada mini game.
The costume changes do not display during the cutscenes in the PS2 and 2007 PC versions of the game (meaning Ada's costume change is never seen because she only appears in cutscenes). In all other versions they do appear.
"Special 2" is a costume unlocked by completing Separate Ways. This set does not display during cutscenes in any versions of the game. "Special 2" is not available in the Gamecube version.
Leon S. Kennedy will appear in a suit, complete with a red tie, fedora, gloves, and a white scarf. His knife is reskinned into a switchblade. This will also change the appearance of the Chicago Typewriter; it will feature a foregrip and the magazine will be changed to an ammo drum. Special animations are given to Leon when reloading the Chicago Typewriter: reloading results in Leon adjusting his hat. Reloading four times in a row results in Leon performing a trick where he throws his hat up and catches it.
Ashley Graham appears in a complete medieval suit of armor. Only part of her face can be seen normally. When aiming a gun at her the face protection lowers itself. The suit makes her invincible to every enemy attack and any attacks by Leon. She also cannot be picked up by enemies, as they will immediately drop her and fall over themselves. When Leon catches Ashley from a fall, the animation will be different than usual, where he will flinch from the weight.
The Special 2 costumes do not appear during cutscenes, except for the second cutscene watching Leon approaching a Ganado household, as well as radio transmissions.
All extra game modes are unlocked by completing the game once. They are;
The Mercenaries - An arcade style minigame where the player can play as different characters to kill enemies within a time limit and aim for a high score.
Assignment: Ada - A short non-canon scenario where the player controls Ada and must collect plaga samples. She has her own starting equipment and it takes place on the beginning parts of the island.
Separate Ways - A large 5 chapter canon scenario that shows Ada's actions during the maingame. The player can save during the game and visit the Merchant. It isn't present in the Gamecube version.
In the German releases of the game (Gamecube, PS2, 2007 PC, Ultimate HD Xbox 360, PS3 and PC Versions) The Mercenaries and Assignment Ada are unavailable due to censoring. (only Available in the 2016 release pc version of the game)
An option that allowed players to rewatch cutscenes. All the maingame scenes are added once the game is complete, and all the Separate Ways scenes are added once that game mode is completed. This is not available in the Gamecube version.
Ada's Report is a short series of video reports by Ada. There are five and each one is unlocked by completing a chapter of Separate Ways