Uroboros Mkono was a specific manifestation of the virally created Uroboros creature, "birthed" from an anonymous test subject in a TriCell laboratory. It is possible that Mkono's transformation was triggered by Excella Gionne, who was watching from an enclosed observation deck, so that the creature, created when the Uroboros virus rejected the DNA of its host, would kill BSAA agents Sheva Alomar and Chris Redfield. It was far more dangerous than the Uroboros Test Subject, being much more aggressive and having two cores. Mkono was defeated through the exploitation of the creature's sensitivity towards extreme heat; the laboratory contained a flamethrower and refueling station originally designed to destroy biohazardous material in case of a leak. Redfield and Alomar used the flamethrower to weaken Mkono and then shot at its exposed vital organs. However it can be brought down by weapons fire. Even on Professional, a well aimed RPG can down it.
Trivia
Uroboros Mkono.
- The word "Mkono" comes from the Swahili word for "arm", which may be a nod toward the grabbing and engulfing nature of the boss.
- Uroboros Mkono is the only Resident Evil 5 creature not to be featured as a figurine, most likely due to its similar appearance to the first Uroboros, other than its larger size within the game.
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