For the Resident Evil 3 (2020) item, see Vaccine Base (RE3 remake).
"Core material used to create the vaccine. It needs to be mixed with the vaccine medium."
— Item examination - English
"ワクチンを作成する主材料だ ワクチン培養液と混合する必要がある "
— Item examination - Japanese

Vaccine Base (ワクチン素剤 (もとざい) wakuchin motozai?) is a key item in Resident Evil 3: Nemesis.


This item can be combined with the Vaccine Medium to create the Vaccine.


This item can be found by Carlos Oliveira in the Room 402 after solving the "hospital shelf" puzzle. The picture of Arklay Mountains, hanging on the wall will fall and the locked safe can be reached after solving the puzzle. The passcode can be found in the Room 401.

Exploring the locked safe, Carlos can read next message: "It's locked with a number-based lock.".

After picking it up, the message can be read in the empty safe "Nothing more.".




Community content is available under CC-BY-SA unless otherwise noted.