Raccoon City's and the Arklay Mountains' wasp population grew to huge sizes thanks to the viral outbreak. Their mutation was mostly limited to an increase in size and general aggression, common with the simpler t-Virus-infected animals.
In Resident Evil
During the Arklay Mountains outbreak caused by James Marcus, normal wasps accidentaly got infected by the t-Virus; this made them grow in size and made them more aggressive to whoever approached their hive. If threatened, they attacked their victim, in masses, with their stings.
During the Raccoon City Outbreak, some Giant Wasps were found by survivors in underground facilities and forest areas as well. The virus also caused their venom to be more powerful, causing the inevitable death of the victim unless the venom was treated with Blue Herbs. Also, their venom, also known as the V-Poison, was one of the three components used to make the Daylight vaccine, an agent that stops the spread of the t-Virus in a host's body, neutralizing it for good.
Resident Evil: The Deck Building GameWasps are Infected cards introduced in the third set Outbreak. They are relatively weak Infected, only having 15 Health and dealing no base damage. They do have an effect however; once they're revealed they deal 20 Damage automatically. Similar to the effects of Set 1's Nemesis-T Type and the Guardian of Insanity, its an effective way to bypass the Level 1 effect of the promotional Chris Redfield card, which nullifies damage from weaker Infected. Its worth only 2 Decorations upon its defeat.
- In the Resident Evil Remake, they can survive getting hit from several weapons, and even a Rocket Launcher shot, eventually a player has to walk on them in order to kill them for good.
- They are more agressive and bigger in the Outbreak Series than they were in Resident Evil (DS, original and Remake).
- Their attack in the Outbreak series will be harder to dodge, as in Resident Evil Remake a player can tap the bottons in order to make the wasps go away.
- A good tactic to kill wasps is to play as Cindy, and when they're in mid-air ready to attack, to dodge and after the wasps passes through, to hit it with a Melee weapon (this has a chance to make the wasp to be stunned and drop in the floor, allowing the player to stomp, shoot or beating it to death) or shoot it.