"William Birkin" may refer to the following:
- William Birkin - an Umbrella researcher in the prime universe
- William Birkin - a character in the Operation Raccoon City universe
- William Birkin - a character in the S.D. Perry universe
- William Birkin - a character in the WildStorm comics universe
- William Birkin- a character in the Anderson movies universe
- Dr. William - a character in the King's Foundation universe
- Dr. William - a character in the SkyWalker universe
- William Birkin - a character in the removed Prototype universe.
- William Birkin (Recollections glossary)
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