(Capcom's primary storyline)
"You really shouldn't have come here. My name's Zoe. There should be a way out through the attic. Go there---now."
— Zoe's first phone call to Ethan.
Zoe Baker (ゾイ・ベイカー Zoi Beikā ) is a woman from Dulvey, Louisiana who was involved in the Dulvey incident, a three-year series of abductions by her parents, Jack and Marguerite Baker, and her brother Lucas, all at the behest of Eveline, a young girl genetically-engineered to control minds.
Zoe lived with the Baker Family on the Plantation in Dulvey, Louisiana, with her parents and older brother Lucas. Zoe did an art project in the fourth grade of her and her family which hung in the dining room. There was an incident where Zoe called Lucas a pervert for watching her do yoga.
"All right, little girl. Let's get you cleaned up."
— Zoe tends to Eveline at her bedside.
On October 9, Lucas found a wrecked tanker washed up in the bayou due to a vicious storm, which Jack investigated the next day. In the wreckage, he found Mia Winters and housed her in the trailer that Zoe was living in. At this time, Zoe watched a news report on the storm in order to get a better understanding of the chaos, but Jack soon returned from the bayou carrying another survivor, Eveline, in his arms, which he suggested should be housed in Lucas' old room. Jack and Marguerite requested Zoe to bring a change of clothes to the girl, tasking her with cleaning the little girl up and making sure she was comfortable. However, before she had a chance to do anything, Eveline caused a blackout in the house and escaped into the darkness.
Believing that the incident was merely just a powercut, Zoe looked throughout the house for Eveline. However, she instead found Lucas lying unconscious on the dining room floor and heard the mumblings of her mother coming from the bathroom. Upon encountering her mother, Zoe was grabbed by Marguerite who muttered about the gift Eveline had given her and tried to force feed her bugs which came from her mouth. Jack came back just in time to save Zoe and restrained his wife, instructing Zoe to retrieve some rope from the garage. When she returned, she found her father trying to drown her mother. Though he seemed normal at first, Jack grabbed her and menaced her by cutting open his chest, claiming that doing so would show devotion to Eveline. Zoe fled from her father, using the rope to hold one of the doors shut and watched as he dragged Lucas to meet Eveline.
Successfully escaping from Jack and Marguerite, Zoe fled to the trailer, where she found another survivor, Mia Winters, lying on the floor. She found a letter on the table and read it, learning about Eveline and finding a strange head. Upon hearing the voice of Eveline, Zoe turned around to find her standing behind her. As the girl grabbed her arm, Zoe fell unconscious.
Zoe then suddenly woke up back at the dining table, convinced that the night she had experienced was simply a dream, and tried to explain it to her family. However, she was abruptly stopped by Jack, who explained plans to prepare for damage following the storm. Soon, Eveline appeared and addressed Zoe as her "sister", shocking her.
Living as an outcast
"I was trapped with those monsters for 3 years---all of them trying to kill me..."
— Zoe tells Joe about her survival on the Baker Ranch.
Unlike the rest of her family, Zoe was able to resist Eveline's mind control due to her knowledge about Eveline, despite being infected and refused to partake in the family's murderous activities, choosing instead to isolate herself from them in her trailer in the yard. Since she now possessed Eveline's "gift", the rest of her family appeared to be content with her isolation from them and made no attempts to force her into being part of their new family. They did however prevent Zoe from escaping the property and did not allow her to snoop into certain part of the house in the attempt to find the cure in Mia's letter. At some point, Zoe had a domestic spat with Marguerite which got so heated that she pulled out a knife that she had hidden on her own mother, having hid other knifes around the main house. Realizing her family was beyond saving, Zoe attempted to cure herself and escape multiple times by assisting her family's kidnap victims in escaping, though none of them survived.
Working with Ethan
"You did good Ethan. Shut up and listen if you want to stay alive. You gotta get out of that house. There might be a way out through the main hall. And that thing on your wrist is a codex. Don't lose it. It's important."
— Zoe's second phone call to Ethan.
When Mia's husband, Ethan, arrived at the plantation following a message sent to him by Mia, Zoe first managed to get in contact with him by telephone, following a struggle between him and Mia in the Guest House. At first, she told him to escape using the attic window, but he was caught by her father before he could do so. Whilst Ethan was unconscious, Zoe reattached his severed hand which had been removed in a scuffle with Mia and gave him a Genome Codex to monitor his health.
After Ethan had escaped Jack and the rest of the family at the dinner table, Zoe contacted him and provided information about the house and hints on where to go. After Ethan escaped the main house on the plantation, apparently killing Jack in the process, he found her trailer and was once again contacted by Zoe who asked him to search the old house for the recipe to a serum which would cure Mia and herself of the infection, all the while warning him of her mother. After Ethan found the recipe, Zoe checked up on Ethan, and after being told by him that they needed a D-Series head and arm, she realized the value of the head she had retrieved from the trailer, and instructed Ethan to find the arm in the Old House.
After Ethan's successful finding of the D-Series arm, Zoe told him to meet her at the trailer, but shortly after she was kidnapped by Lucas and taken to the Boathouse alongside Mia as a captive.
She was eventually freed once Ethan had managed to outsmart and scare off Lucas, and now having the two ingredients she needed for the serum, she crafted two vials which she gave to Ethan. However, Ethan was soon grabbed and taken away by a heavily mutated Jack, requiring Zoe and Mia to flee to safety. As Ethan struggled to keep Jack down, Zoe suggested that he use one of the serums on Jack, which calcified him and successfully stopped his attacks.
Having only one serum left after the encounter, Ethan had to make a choice between curing Zoe or his wife Mia. Ethan ultimately chose to cure Mia, which made Zoe feel betrayed and made her angrily demand the two to leave without her, despite Ethan's promise that he will send help for her.
During Ethan's vision while trapped in the mold, Zoe was seen sitting alongside her father Jack, but did not speak at all to him during this vision.
End of Zoe
"Ya gotta know, deep down somewhere, they were still your family and they loved you. Especially your daddy...even in his final days."
— Joe explaining to his niece that her family weren't themselves, but loved her nonetheless.
As punishment for helping Ethan and Mia to try and escape, Zoe was calcified by Eveline, but remained alive. Following his rescue, Ethan asked Chris Redfield and Blue Umbrella to look for and rescue Zoe. Weeks after the escape and Eveline's death, Blue Umbrella's special forces team surveyed the Baker Ranch and the surrounding bayou and eventually found her, but were soon apprehended by her uncle Joe, who took her and one of the Umbrella soldiers to his cabin in the swamp in hopes of saving her from the infection. However, despite Joe's initial efforts resulting in finding a partial dose of the cure, it was not enough to fully cure her.
Zoe remained unconscious during the time Joe looked for her cure, with Joe taking her to an Umbrella camp in hopes of finding a full cure. However, during this time Joe was pursued by her father Jack, now under the guise of the Swamp Man, and she was soon kidnapped by her father and used as bait to lure Joe into a trap in one of the churches in the bayou.
Soon after, she was taken back to the Baker's main house, now another Umbrella camp, eliminating all Umbrella forces in his way and setting her up at the dinner table. However, upon Joe's arrival, she was tossed aside as they both had one final encounter which Joe was able to win. Joe finally managed to cure her by the time Chris Redfield and other Umbrella backup forces arrived.
Ethan later called a recovering Zoe, during which she thanked him for keeping his promise and sending help.
In the main game, she only interacts with Ethan by communicating with him through the telephones that are scattered throughout the Baker ranch.
- If Ethan chooses to save Zoe, they leave in the boat and watch as they leave Mia behind. As they follow downstream, Zoe reveals to Ethan how she and her family had become infected. As they reach the shipwreck in the swamp, Ethan, wanting to find out what had happened, stopped the boat to explore. However, before he can leave, Eveline attacks them. Begging her to stop, Zoe is killed when Eveline calcifies her body, killing her. Her body is presumably completely destroyed when the boat was capsized. The End of Zoe DLC confirmed that this is non-canon.
- Regardless of Ethan's choice, Zoe also appeared in Ethan's contact with her father, her mind still linked to Eveline's consciousness.
- Zoe was the unseen figure who calls the protagonist in the Beginning Hour demo, in a similar manner to how she contacts Ethan though her voice lacks the southern accent featured in the game. She would only call after the player had explored the house and obtained the basement key; the only way to reach her was the house phone in the attic. However, as of the final December 2016 update, Zoe will no longer contact the protagonist and in the final version of the game, Zoe says Ethan is the only person she saw escape from the Bakers' house.
- Prior to Ethan's arrival, Zoe has helped previous victims of the Baker family in an attempt to escape the house, with every one of them meeting an unfortunate end. Annoyed by this, Jack prevented the would-be survivors from reaching her trailer by hiding the three reliefs.